Results 101 to 110 of about 3,166,049 (353)

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

open access: yesFEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita   +3 more
wiley   +1 more source

Which Quantum Theory Must be Reconciled with Gravity? (And What Does it Mean for Black Holes?)

open access: yesUniverse, 2016
We consider the nature of quantum properties in non-relativistic quantum mechanics (QM) and relativistic quantum field theories, and examine the connection between formal quantization schemes and intuitive notions of wave-particle duality.
Matthew J. Lake
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Thinking Non Locally: The Atemporal Roots of Particle Physics

open access: yesFrontiers in Physics, 2018
Developing an approach defined in previous papers a correspondence between elementary particles and elements of a particular set of directed graphs said “glyphs” is made explicit.
Leonardo Chiatti
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

O Modelo Padrão da Física de Partículas

open access: yesRevista Brasileira de Ensino de Física
Inicialmente, apresenta-se, de modo simplificado, o Modelo Padrão como uma teoria sofisticada que identifica as partículas elementares e suas interações.
Marco Antonio Moreira
doaj   +1 more source

Elementary Particles and the Causet Approach to Discrete Quantum Gravity

open access: yes, 2014
In a previous paper, the author introduced a covariant causet ($c$-causet) approach to discrete quantum gravity. A $c$-causet is a finite partially ordered set that is invariant under labeling.
Gudder, Stan
core  

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo   +13 more
wiley   +1 more source

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