Results 61 to 70 of about 19,168 (260)

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

2 TeV walking technirho at LHC?

open access: yesPhysics Letters B, 2015
The ATLAS collaboration has recently reported an excess of about 2.5 σ global significance at around 2 TeV in the diboson channel with the boson-tagged fat dijets, which may imply a new resonance beyond the standard model.
Hidenori S. Fukano   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

A física da terapia de captura de nêutrons pelo boro

open access: yesRevista Brasileira de Ensino de Física
Neste artigo fazemos uma breve exposicão de como um dos conceitos fundamentais da física nuclear fissão nuclear e seus produtos tem aplicação na medicina, na chamada terapia de captura do nêutron pelo boro (BNCT na sigla em inglês).
A.C. Bruno-Machado   +2 more
doaj   +1 more source

CONFORMAL GEOMETRY AND ELEMENTARY PARTICLES

open access: yesProceedings of the National Academy of Sciences, 1954
The kinematical consequences of basing (classical or quantum) field theory on the conformal geometry are examined in this paper. The space in question is that of all spheres inR 4 (flat 4-space of signature (+++−)); the fundamental invariant, the angle under which two spheres intersect.
openaire   +4 more sources

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

O Modelo Padrão da Física de Partículas

open access: yesRevista Brasileira de Ensino de Física
Inicialmente, apresenta-se, de modo simplificado, o Modelo Padrão como uma teoria sofisticada que identifica as partículas elementares e suas interações.
Marco Antonio Moreira
doaj   +1 more source

On the motion of bodies based on changes in the kinetic moment

open access: yesRUDN Journal of Engineering Research, 2019
The controlled motion of a body in a central gravitational field without mass flow is considered. The possibility of moving the body in the radial direction from the center of attraction due to changes in the kinetic moment relative to the center of mass
Yury N. Razoumny, Sergei A. Kupreev
doaj   +1 more source

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