Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test. [PDF]
J Vis Exp, 2018 The elevated plus maze test is a behavioral test for assessing animal anxiety in rodents. Although this test is widely applied in the field of behavioral science, conflicting outcomes are often provided from different laboratories.
Horii Y, McTaggart I, Kawaguchi M.
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Behavior of Male and Female C57BL/6J Mice Is More Consistent with Repeated Trials in the Elevated Zero Maze than in the Elevated Plus Maze. [PDF]
Front Behav Neurosci, 2017 The elevated plus maze (EPM) and elevated zero maze (EZM) are behavioral tests that are widely employed to assess anxiety-like behaviors in rats and mice following experimental manipulations, or to test the effects of pharmacological agents.
Tucker LB, McCabe JT.
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Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats. [PDF]
Pharmacol Biochem Behav, 2021 Knight P +5 more
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Myristic acid produces anxiolytic-like effects in Wistar rats in the elevated plus maze. [PDF]
Biomed Res Int, 2014 A mixture of eight fatty acids (linoleic, palmitic, stearic, myristic, elaidic, lauric, oleic, and palmitoleic acids) at similar concentrations identified in human amniotic fluid produces anxiolytic-like effects comparable to diazepam in Wistar rats ...
Contreras CM +5 more
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Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests [PDF]
Brazilian Journal of Medical and Biological Research, 2009 The endocannabinoid system is involved in the control of many physiological functions, including the control of emotional states. In rodents, previous exposure to an open field increases the anxiety-like behavior in the elevated plus-maze.
A. Ribeiro +3 more
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The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
Nature Protocols, 2007 Alicia A Walf, Cheryl A Frye
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Deuterium depletion induces anxiolytic-like effects in rats [PDF]
Archives of Biological Sciences, 2014 Deuterium-depleted water (DDW) has a concentration of deuterium 6-7 times lower than naturally occurring water (20-25 ppm vs. 150 ppm). When administered for a longer period, it can reduce the concentration of deuterium throughout the body ...
Mladin Cristian +4 more
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Neuropharmacological evaluation and HPTLC fingerprint profile of phytocompound-enriched chloroform fraction of methanolic extract of Lagenaria siceraria (Molina) Standley fruits – a potent Asian ethno-medicinal vegetable plant [PDF]
Folia Medica, 2022 Introduction: Lagenaria siceraria (Molina) Standley (Cucurbitaceae) is a traditional vegetable plant, popularly known as bottle gourd (English) and lauki (Hindi). It is a climbing herb characterized with a number of therapeutic properties.
Sachin Parmar +2 more
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Effects of subchronic phencyclidine on behaviour of female rats on the elevated plus maze and open field [PDF]
, 2009 YesFemale hooded-Lister rats received either sub-chronic phencyclidine (PCP) (2 mg/kg, n=20) or vehicle (1 ml/kg, n=20) i.p. twice daily for seven days, followed by a seven-day washout period. Rats were challenged with acute PCP or vehicle and tested for
Abekawa, T. +3 more
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Anxiolytic activity of Berberis aristata root extract in mice
BLDE University Journal of Health Sciences, 2020 BACKGROUND: Anxiety is a common emotional response in humans and it is one of most common psychiatric illnesses. Interest in herbal drugs is growing nowadays for the optimum treatment of anxiety. The aim of the present study was to explore the anxiolytic
Divya Goel
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