Results 51 to 60 of about 106,332 (235)

Bioactivity guided isolation of apigenin from Stachys lavandulifolia Vahl. in mice with anxiolytic effects [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Stachys lavandulifolia is traditionally used for the treatment of anxiety. Our previous study showed that the ethyl acetate fraction of the plant had substantial anxiolytic action in mice. The present study was aimed to investigate the main
Mohammad Rabbani, Seyed-Ebrahim Sajjadi, Masoumeh Karimi-Firozjai, Mostafa Ghannadian   +3 more
doaj   +1 more source

Anxiolytic-like effects of mitragynine in the open-field and elevated plus-maze tests in rats

Journal of Physiological Sciences, 2014
The effects of mitragynine on anxiety-related behaviours in the open-field and elevated plus-maze tests were evaluated. Male Sprague–Dawley rats were orally treated with mitragynine (10, 20 and 40 mg/kg) or diazepam (10 mg/kg) 60 min before behavioural ...
A. I. Hazim, S. Ramanathan, S. Parthasarathy, M. Muzaimi, S. Mansor   +4 more
semanticscholar   +1 more source

Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. [PDF]

, 2018
Microglia are the main immune component in the brain that can regulate neuronal health and synapse function. Exposure to cosmic radiation can cause long-term cognitive impairments in rodent models thereby presenting potential obstacles for astronauts ...
Campbell-Beachler, Mary, Chou, Austin, Feng, Xi, Grue, Katherine, Jones, Tamako, Krukowski, Karen, Nelson, Gregory, Paladini, Maria Serena, Riparip, Lara-Kirstie, Rosi, Susanna, Sacramento, Kristen   +10 more
core   +2 more sources

Removal of GABAA receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations [PDF]

, 2011
We investigated the behavioral significance of fast synaptic inhibition by αβγ2-type GABA(A) receptors on parvalbumin (Pv) cells. The GABA(A) receptor γ2 subunit gene was selectively inactivated in Pv-positive neurons by Cre/loxP recombination.
Leppa, E., Linden, A., Vekovischeva, O., Swinny, Jerome, Rantanen, V., Toppila, E., Hoger, H., Sieghart, W., Wulff, P., Wisden, W., Korpi, E.   +10 more
core   +1 more source

Anxiolytic Effect of L-carnitine in Adult Male Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives: The beneficial effect of L-carnitine for treatment of neurological diseases has been investigated in various studies. The aim of the present study was to investigate the effect of L-carnitine supplement on anxiety behavior in ...
Zahra Sasaninejad, Maryam Eidi, Reza Ghahramani, Zeinab Ahmarinejad, Ali Rezaei Galeshpol, Fatemeh Rasoulian, Ali Ilchizadeh Kavgani, Marzieh Hajizadeh   +7 more
doaj  

Evaluation of Anxiolytic-like Effects of Some Short-Acting Benzodiazepine Hypnotics in Mice

Journal of Pharmacological Sciences, 2008
Anxiolytic-like effects of some short-acting benzodiazepine hypnotics were examined with experimental paradigms of anxiety using an elevated plus-maze in male ICR mice. Diazepam was used as a positive control.
Tomomi Nishino, Tomoko Takeuchi, Kenshi Takechi, Chiaki Kamei   +3 more
doaj   +1 more source

Elevated plus-maze behavior in adult offspring of selectively bred rats

Physiology & Behavior, 1996
Animals sampled from the third generation (S3) of selective breeding of N:NIH strain rats based on ultrasonic vocalization (USV) rates in infancy (High, Low, and Random lines) were tested as adults on the elevated plus maze, a well-validated test of anxiety.
G S, Dichter, S A, Brunelli, M A, Hofer
openaire   +2 more sources

Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors [PDF]

, 2015
Delta-9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, induces numerous undesirable effects, including memory impairments, anxiety, and dependence.
A Busquets-Garcia, A Castañé, A Kern, A Manglik, A Pazos, A Pertovaara, A Zimmer, AC Magalhaes, AJ Venkatakrishnan, AL Bodor, Antoni Pastor, AR Best, Arnau Cordomí, BB Gorzalka, C Bombardi, C Castellano, C Ferrada, C Sanchis-Segura, Carmen Lluís, CP Vandermaelen, E Aso, E Fiorica-Howells, E Moreno, E Moreno, E Moreno, E Palazzo, E Puighermanal, E Puighermanal, E Valjent, Enric I. Canela, Eric J. Nestler, Estefanía Moreno, ET Weber, F Berrendero, F Rodríguez de Fonseca, F Simonin, F Steindel, FA Moreira, G Di Chiara, G Mengod, G Paxinos, G Porras, G Soria, Gemma Navarro, GM Thomas, HY Meltzer, J De Almeida, J González-Maeso, J González-Maeso, JC Parrish, JF Cheer, JF López-Giménez, JF López-Giménez, JJ Rodriguez, JM Franklin, JM Walker, JR Clapper, K Baba, K Mackie, K Monory, K Tsou, K Tsou, KA Gleason, L a. H Miner, L Callén, L Lanfumey, Laurence Lanfumey, Leonardo Pardo, Lesley A. Howell, LJ Sim-Selley, LP Martin, LTO Lee, M Bouvier, M Fribourg, M Lüttgen, M Schneider, M-M Mocanu, MJ Orejarena, N Kabli, NA Darmani, NB Eddy, NV Weisstaub, O Söderberg, P Pacher, P Rivera, Paola Gasperini, Patricia Robledo, Peter J. McCormick, R Franco, R Maldonado, R Mechoulam, R Mongeau, R Nygaard, R Schroder, Rafael de La Torre, Rafael Maldonado, RL Jakab, S Ferre, S Ferré, S Ferré, S González, S Haj-Dahmane, S Mato, S Pellow, SGF Rasmussen, SGF Rasmussen, SM Eggan, T Issad, T-W Chen, V Mendizábal, X Guitart, Xavier Viñals, Y-C Chiang   +112 more
core   +6 more sources

Evaluation the effect of neuropeptide of Bombesin on modulation of anxiety reaction in mice

مجله دانشگاه علوم پزشکی گرگان, 2007
Background & Objective: Bombesin (BBS) is a tetra-decapeptide amino acid neuropeptide in central nervous system within a variety of mammalian species. Also it has many biological effects that may be effective in modulation of anxiety.
AA Vafaei, AA Taherian, A Rashidy-Pour
doaj  

Comparison of Various Dosages of Escitalopram on Anxiety-like Behavior and Body Weight in Male Rats under Severe Chronic Stress

Advanced Biomedical Research
Background: Stress and escitalopram impact mood and various physiological systems. The present study aimed to compare the protective effects of different dosages of escitalopram on anxiety-like behavior and body weight in male rats subjected to severe ...
Maryam Radahmadi, Zahra Farahbakhsh
doaj   +1 more source