Results 71 to 80 of about 96,533 (188)

Dorsal Hippocampus ERK2 Signaling Mediates Anxiolytic-Related Behavior in Male Rats

Chronic Stress, 2019
Background Anxiety disorders are the most common neuropathologies worldwide, but the precise neuronal mechanisms that underlie these disorders remain unknown.
Jorge A. Sierra-Fonseca, Lyonna F. Parise, Francisco J. Flores-Ramirez, Eden H. Robles, Israel Garcia-Carachure, Sergio D. Iñiguez   +5 more
doaj   +1 more source

Effect of benzene on the cerebellar structure and behavioral characteristics in rats

Asian Pacific Journal of Tropical Biomedicine, 2015
Objective: To investigate the effects of benzene on rat's cerebellum structure and behavioral characteristics, including anxiety and motor impairment.
Ali Rafati, Mahboobeh Erfanizadeh, Ali Noorafshan, Saied Karbalay-Doust   +3 more
doaj   +1 more source

The ontogeny of exploratory behavior in male and female adolescent rats (Rattus norvegicus) [PDF]

, 2009
Supported by Wellcome Trust grant 078405/Z/05/ZDuring adolescence, rats gain independence from their mothers and disperse from the natal burrow, with males typically dispersing further than females. We predicted that, if dispersal patterns are associated
Aguilar, Arnett, Beatty, Bertoglio, Blakemore, Blizard, Brown, Byrnes, Calhoun, Candland, Carola, Crews, Denenberg, Dingemanse, Elliott, Estanislau, Fraňková, Hall, Hall, Handley, Hefner, Ho, Imhof, Izídio, Johnston, Jonasson, Krebs, Lalonde, Leussis, Masur, McCormick, Montgomery, Pellow, Philpot, Prut, Saucier, Selinger, Seymoure, Sisk, Slob, Spear, Spear, Stevens, Stewart, Tapert, Tirelli, Tropp, Vallée, Walf, Williams, Williams   +50 more
core   +2 more sources

Pharmacological effect of one icv dose of Allopregnanolone in female rat: behavioural profile [PDF]

, 2015
We have previously observed that intracerebroventricular allopregnanolone (ALLO) injection produced an anxiolytic effect and inhibited sexual receptivity when the test was performed in a separate manner. Also, ALLO reverts learning deficit in female rats
Cabrera Kreiker, Ricardo Jorge, Escudero, Carla Gimena, García Menéndez, Sebastián Marcelo Manuel, Giuliani, Fernando Alfredo, Laconi, Myriam Raquel, Pelegrina, Laura Tatiana   +5 more
core  

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Bioactivity guided isolation of apigenin from Stachys lavandulifolia Vahl. in mice with anxiolytic effects [PDF]

Journal of HerbMed Pharmacology, 2018
Introduction: Stachys lavandulifolia is traditionally used for the treatment of anxiety. Our previous study showed that the ethyl acetate fraction of the plant had substantial anxiolytic action in mice. The present study was aimed to investigate the main
Mohammad Rabbani, Seyed-Ebrahim Sajjadi, Masoumeh Karimi-Firozjai, Mostafa Ghannadian   +3 more
doaj   +1 more source

modCHIMERA: A novel murine closed-head model of moderate traumatic brain injury [PDF]

, 2018
Traumatic brain injury is a major source of global disability and mortality. Preclinical TBI models are a crucial component of therapeutic investigation.
Bayly, P. V., Brody, D. L., Fanizzi, C., Gangolli, M., Kim, J. H., Kummer, T. T., Sauerbeck, A. D., Wellington, C. L.   +7 more
core   +2 more sources

Antidepressant and anxiolytic activity of Lavandula officinalis aerial parts hydroalcoholic extract in scopolamine-treated rats

Pharmaceutical Biology, 2017
Context: Anxiety and depression are common in Alzheimer’s disease (AD). Despite some evidence, it is difficult to confirm Lavandula officinalis Chaix ex Vill (Lamiaceae) as an anxiolytic and antidepressant drug. Objective: The effects of L.
Batool Rahmati, Zahra Kiasalari, Mehrdad Roghani, Mohsen Khalili, Fariba Ansari   +4 more
doaj   +1 more source

Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through aß¿2-type GABA(A) Receptors [PDF]

, 2011
Peer reviewedPublisher ...
Korpi, Esa R, Leppä, Elli, Linden, Anni-Maija, Lüddens, Hartmut, Schmitt, Ulrich, Wisden, William, Wulff, Peer   +6 more
core   +3 more sources

Modulation of Anxiety-Like Behavior in Sildenafil Citrate-Treated Mice Placed in an Elevated Plus-Maze

Basic and Clinical Neuroscience, 2011
Introduction: Sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, may have various effects on the central nervous system via the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway.
Siamak Shahidi, Nasrin Hashemi-Firouzi, Minoo Mahmoodi   +2 more
doaj   +2 more sources