Results 81 to 90 of about 96,533 (188)

Anxiolytic and antidepressant effects of tarragon (Artemisia dracunculus L.) hydro-alcoholic extract in male rats exposed to chronic restraint stress

open access: yesیافته‌های نوین در علوم زیستی, 2017
Tarragon (Artemisia dracunculus L.) has antioxidant, anti-diabetic, anti-bacterial and anti-inflammatory proper-ties. The aim of this study was to evaluate the effect of tarragon hydro-alcoholic extract on anxiety and depression in male rats exposed to ...
Hajar Khosravi   +2 more
doaj  

Gut Dysbiosis and Neurobehavioral Alterations in Rats Exposed to Silver Nanoparticles

open access: yes, 2017
Due to their antimicrobial properties, silver nanoparticles (AgNPs) are being used in non-edible and edible consumer products. It is not clear though if exposure to these chemicals can exert toxic effects on the host and gut microbiome.
Bivens, Nathan J.   +10 more
core   +1 more source

Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness [PDF]

open access: yes, 2019
Gulf War Illness (GWI) is a chronic multi-symptom disorder afflicting the veterans of the First Gulf War, and includes neurological symptoms characterized by depression and memory deficits.
Blair, Robert   +3 more
core   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

open access: yes, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N   +20 more
core   +2 more sources

GPR30 activation decreases anxiety in the open field test but not in the elevated plus maze test in female mice

open access: yesBrain and Behavior, 2013
The GPR30 is a novel estrogen receptor (ER) that is a candidate membrane ER based on its binding to 17β estradiol and its rapid signaling properties such as activation of the extracellular‐regulated kinase (ERK) pathway.
D. Anchan   +3 more
semanticscholar   +1 more source

Study of the effect of extract of Thymus vulgaris on anxiety in male rats

open access: yesJournal of Traditional and Complementary Medicine, 2016
There is some evidence in traditional medicine for the effectiveness of Thymus vulgaris (百里香 bǎi lǐ xiāng) in the treatment of anxiety in humans. The elevated plus-maze (EPM) has broadly been used to investigate anxiolytic and anxiogenic compounds.
Alireza Komaki   +3 more
doaj   +1 more source

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior [PDF]

open access: yes, 2015
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Borevitz, Justin O.   +13 more
core   +2 more sources

Stressor- and Corticotropin releasing Factor-induced Reinstatement and Active Stress-related Behavioral Responses are Augmented Following Long-access Cocaine Self-administration by Rats [PDF]

open access: yes, 2008
Rationale Stressful events during periods of drug abstinence likely contribute to relapse in cocaine-dependent individuals. Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing
AM Basso   +62 more
core   +2 more sources

Early handling and repeated cross-fostering have opposite effect on mouse emotionality [PDF]

open access: yes, 2015
Early life events have a crucial role in programming the individual phenotype and exposure to traumatic experiences during infancy can increase later risk for a variety of neuropsychiatric conditions, including mood and anxiety disorders.
Battaglia, M   +6 more
core   +2 more sources

THE EFFECTS OF FLUOXETINE IN THE ELEVATED PLUS MAZE TEST

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
W e have studied the effects of fluoxetine, a selective serotonin reuptake inhibitor, on anxiety by using elevated plus m aze tc in m ice. A cute intraperitoneal adm inistration of fluoxetine (20 m g/kg) decreased the time spent in the open arm s ...
Mehmet KURT   +3 more
doaj  

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