Results 211 to 220 of about 96,671 (319)

The Rostral Ventrolateral Medulla Input to Central Amygdala Regulates Anxiety‐Like Behaviors in Mice for Chronic Light Exposure

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Jing et al. demonstrate that the CeA receives input from the RVLM in normal mice, and the chronic light exposure induced more pronounced elevated neuronal activity in the RVLM than the CeA. The enhanced excitatory input from the RVLM to CeA induced anxiety‐like behaviors in mice, revealing a novel circuit by which the RVLM regulates light‐related ...
Jia‐Ni Jing, Xing Tan, Chou Xu, Chao Yuan, Hao Fan, Wei‐Zhong Wang   +5 more
wiley   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher T. Minson   +5 more
wiley   +1 more source

Relationship between ethanol-induced activity and anxiolysis in the open field, elevated plus maze, light-dark box, and ethanol intake in adolescent rats

Behavioural Brain Research, 2014
M. B. Acevedo, Michael E. Nizhnikov, J. C. Molina, R. Pautassi   +3 more
semanticscholar   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

Glia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips, Emily G. Thompson, Olivia Spead, Balaji G. Vijayakumar, Erica R. Kent, Sean J. Miller, Treasure Nwokeleme, Svetlana Vidensky, Mohamed Hassan Farah, Jeffrey D. Rothstein   +9 more
wiley   +1 more source

Behavioral and pharmacological investigation of anxiety and maternal responsiveness of postpartum female rats in a pup elevated plus maze. [PDF]

Behav Brain Res, 2015
Yang Y, Qin J, Chen W, Sui N, Chen H, Li M.   +5 more
europepmc   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao, Zengguang Wang, Hanwen Chang, Yongjin Li, Binbin Wang, Xinfa Shao, Yuxin Zhang, Yixuan Lin, Xinlin Jia, Xianhao Zhou, Wentao Li, Dinghao Luo, Tanjun Deng, Xingzuan Lin, Chen Xu, Yaokai Gan, Dongyun Gu   +16 more
wiley   +1 more source

Yohimbine anxiogenesis in the elevated plus maze requires hindbrain noradrenergic neurons that target the anterior ventrolateral bed nucleus of the stria terminalis

European Journal of Neuroscience, 2013
Huiyuan Zheng, L. Rinaman
semanticscholar   +1 more source