Results 221 to 230 of about 96,671 (319)

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo   +11 more
wiley   +1 more source

Mitochondrial Intercellular Transfer via Platelets After Physical Training Exerts Neuro‐Glial Protection Against Cerebral Ischemia

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Treadmill training protects against white matter injury and reduces cerebral infarction. Muscle‐derived mitochondrial transfer via platelets is promoted by treadmill training. Platelet transfusion emerges as a potential low‐risk therapeutic strategy for sequelae and vascular dementia.
Toshiki Inaba   +8 more
wiley   +1 more source

Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
In D‐galactose‐induced aging model, periodic therapeutic phlebotomy exerts significant and comprehensive anti‐aging effects by inducing bone marrow microenvironment restoration, which rebalances hematopoiesis to restore peripheral blood function and ameliorate systemic aging phenotypes.
Ji‐Ru Cai   +7 more
wiley   +1 more source

Secretome Profiling of Young Multipotent Stem Cells Reveals Angiogenic and Immunomodulatory Mechanisms Supporting Aged Neuromuscular Health

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Young multipotent muscle‐derived stem/progenitor cells (MDSPCs) secrete a unique profile of pro‐angiogenic and immunomodulatory proteins that are diminished with age. Systemic transplantation of young MDSPCs into naturally aged mice activates pathways in neuromuscular tissues, enhancing health and driving molecular, structural, and functional ...
Seth D. Thompson   +5 more
wiley   +1 more source

The behaviour–performance continuum: how does individual variation in locomotor abilities relate to behaviour?

open access: yesBiological Reviews, Volume 101, Issue 1, Page 486-518, February 2026.
ABSTRACT A series of terminological, technical, conceptual, and statistical challenges present themselves when trying to study correlations between measures of performance abilities (what an animal can do) and behavioural traits (what an animal chooses to do).
Vincent Careau   +3 more
wiley   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin   +6 more
wiley   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao   +15 more
wiley   +1 more source

Population Genomics of a Rare and a Common Wood–Inhabiting Fungal Species Across Europe

open access: yesMolecular Ecology, Volume 35, Issue 3, February 2026.
ABSTRACT Many species have become threatened during the Anthropocene, requiring conservation strategies based on biological evidence. Wood‐inhabiting fungi face multiple threats due to a complex interplay of a short lifespan, removal of dead wood as a resource and climate change.
Franz‐Sebastian Krah   +23 more
wiley   +1 more source

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