Results 221 to 230 of about 2,062,774 (354)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dynamic stability of climate-growth relationships in <i>Picea crassifolia</i> in the Qilian Mountains: the modulating role of elevation gradient and time-varying characteristics. [PDF]

Front Plant Sci
Zhao J, Gao Y, Wu X, Ren X, Ma X, Yuan H, Zhao W, Zhao N, Vrahnakis M, Kastridis A, Wei N, Jing W.   +11 more
europepmc   +1 more source

Landform Classification Using Digital Elevation Model by the Skills of Image Processing

, 1995
Junko Iwahashi, Izumi Kamiya
openalex   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Subglacial water flow and ice dynamics during glacial lake outburst floods observed from space. [PDF]

Nat Commun
Magnússon E, Drouin V, Pálsson F, Jóhannesson T, Belart JMC, Wuite J, Tolpekin V, Hannesdóttir K, Berthier E, Sigurðsson G, Einarsson B, Ófeigsson BG, Nagler T, Gudmundsson MT, Högnadóttir T.   +14 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Prolonged ST-Segment Elevation and Persistent Left Ventricular Dysfunction Assessed by Dual-Isotope Myocardial Scintigraphy in Takotsubo Syndrome: A Case Report. [PDF]

Cureus
Kurisu S, Fujiwara H.
europepmc   +1 more source

Bizarre st elevation

The Anatolian Journal of Cardiology, 2018
Akbal, Özgür Yaşar, Keskin, Berhan, Hakgör, Aykun, Karagöz, Ali   +3 more
openaire   +2 more sources

Using Water Energy for Electrical Energy Conservation by Building of Micro hydroelectric Generators on The Water Pipelines That Depend on The Difference in Elevation

, 2011
Mohammed Taih Gatte, Rasim Azeez Kadhim, Farhan Leftah Rasheed   +2 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source