Results 201 to 210 of about 56,421 (241)

Isolation, Insularity and Resilience: A Review of the Geophysical, Socioeconomic, and Environmental Vulnerabilities of Gran Canaria and Lesvos Islands for Policy Interventions to Global Change

Sustainable Development, EarlyView.
ABSTRACT The dynamic nature of small islands being geographically isolated and their perceived connectedness with global networks complicates research attempts to draw general conclusions on whether insularity leads to marginalization or strengthens their resilience for sustainable development.
Toheeb Lekan Jolaosho, Mazen Marouani, Takwa Boughanmi   +2 more
wiley   +1 more source

Integrated Capsaicin‐Functionalized Superhydrophobic Photothermal Coating for Sustainable Antifouling Control at the Air‐Seawater Interface

Small, EarlyView.
An integrated capsaicin‐functionalized superhydrophobic photothermal coating combines covalently immobilized bioactive functionality and Cassie‐state anti‐adhesion with CNT‐enabled solar heating. This dual‐mode strategy passively suppresses fouling in the dark and promotes photothermal inactivation and detachment under sunlight, delivering broad ...
Kang Feng, Jiaying Li, Saad Alshammari, Sheng Li, Yue Ma, Yan Li, Shaaban M. Shaaban, Zeinhom M. El‐Bahy, Yiyong Mai, Yusuke Yamauchi, Xingtao Xu   +10 more
wiley   +1 more source

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

Smart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Anatomical factors of the sinuses significantly impact the progression of chronic rhinosinusitis (CRS). This study aims to investigate the correlation between morphological sinus features and the risk of CRS onset to provide evidence‐based support for clinical management.
Song Luo, Xiang‐Hai Hu, Min Yin, Song Li, Lei Cheng   +4 more
wiley   +1 more source

Unraveling the impact of dog‐friendly spaces on urban–wildland pumas and other wildlife

Wildlife Biology, EarlyView.
As the most widespread large carnivore on the planet, domestic dogs Canis lupus familiaris can pose a major threat to wildlife, even within protected areas (PAs). Growing human presence in PAs, coupled with increasing pet dog ownership underscores the urgency to understand the influence of dogs on wildlife activity and health.
Alys Granados, Zara McDonald, Katie McPherson, David Stoner   +3 more
wiley   +1 more source

Cortisol concentrations in hair are biomarkers of health status and seasonal change, but not urbanisation, in wolves

Wildlife Biology, EarlyView.
Wolves have reclaimed much of their former range in Europe, including areas with a high human footprint, yet the physiological impacts of human‐associated stressors remain poorly understood. We first examined methodological factors affecting hair cortisol concentrations (HCC) in wolves by using a ‘shave/re‐shave' design to assess hair growth rate and ...
Gwendolyn Wirobski, Carmela Musto, Rudy Brogi, Martina Lazzaroni, Rupert Palme, Yasmina Wukovich, Fanni Kertész, Ágnes Szabó, Chiara Garbarino, Marco Gobbi, Lorella Barca, Mauro Delogu, The Wolf Network, Friederike Range, Marco Apollonio, Sarah Marshall‐Pescini   +15 more
wiley   +1 more source