ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
From Exposed to Encapsulated: Structural Evolution and Enhanced Stability of Sn-Doped Gold Clusters, SnAu <b><sub>n</sub></b> (<i>n</i> = 2-20), Revealed by DFT. [PDF]
Zhu BC, Deng PJ, Bao L, Liu CJ.
europepmc +1 more source
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard +33 more
wiley +1 more source
Shielding the First 24 Postnatal Months of Life: A Proposal for a Prospective Cohort Study of Early-Life Electromagnetic Exposure and Autism Risk. [PDF]
Garoli A, Greco A.
europepmc +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Relative Interacting Atomic Energy Analysis of the Anomeric Effect in Cyclic and Acyclic O-C-X Systems. [PDF]
Domingo LR +2 more
europepmc +1 more source
Impact of extremely low frequency electromagnetic fields exposure on sleep quality and mental health in a Tunisian power plant: a cross-sectional study. [PDF]
Kacem I +9 more
europepmc +1 more source
Upcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice. [PDF]
Newsome PN, Ajaz S.
europepmc +1 more source
First-Principles Study of the Superconductivity of Ti<sub>3</sub>VH<sub>12</sub> and TiV<sub>3</sub>H<sub>12</sub> Under 200 GPa. [PDF]
Luo J, Wei Q, Zhang M.
europepmc +1 more source

