Results 121 to 130 of about 59,095 (264)

Comparative Effectiveness of Disease-Modifying Treatments in Double Seronegative Neuromyelitis Optica Spectrum Disorder. [PDF]

Neurol Neuroimmunol Neuroinflamm
Mahler JV, Vallejos GB, Mikami T, Bilodeau PA, Anderson M, Drosu N, Bobrowski-Khoury N, Silva GD, Solti M, Apóstolos-Pereira SL, Callegaro D, Leles Vieira de Souza B, Manzano GS, Vishnevetsky A, Gillani R, Pasquale O, Kim A, Vij R, Kister I, Gibbons EL, Jacob A, Huda S, Said Y, Krett JD, Sotirchos ES, Ramprasad M, Abboud H, Crelier VTC, Santos GD, Uawithya E, Siritho S, Sezen A, Altintas A, Gai F, Guo Y, Bhattacharyya S, Levy M, Matiello M.   +37 more
europepmc   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

May-Thurner Syndrome and Its Possible Influence on Pulmonary Embolism Severity: A Case Report. [PDF]

Cureus
Nabhan E, Naoum Nehme E, Vana AP, Poulos N.   +3 more
europepmc   +1 more source

Temporally Delayed Deployment of Photo‐Responsive Liquid Crystal Polymer Networks Toward Neural Interfaces

Advanced Healthcare Materials, EarlyView.
Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng, Eleanor Nguyen Jeakle, Mahjabeen Javed, Rajasree Gopala Krishnan, Thomas J. Smith, Yoo Jin Lee, Sahana Dhananjayan, Sasha M. George, Manivannan Sivaperuman Kalairaj, Ali Hasan Zuaiter, Majed O. Althumayri, Hatice Ceylan Koydemir, Joseph J. Pancrazio, Taylor H. Ware   +13 more
wiley   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Genetic Diversity of Polymyxin Resistance Genes in Klebsiella pneumoniae Clinical Isolates. [PDF]

Mol Ecol
Serwy DM, Conde MER, Alencar ALC, Novaes RLM, Lima-Junior JDC, da Mota FF, Carvalho-Assef AP, Galvao TC, Zahner V.   +8 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Author Correction: Whole-body CD8⁺ T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study. [PDF]

Nat Commun
de Boer JW, Keijzer K, van Doesum JA, Smit NAM, Brouwers AH, van Sluis J, Lub-de Hooge MN, Pierik FR, Huls GA, van Dijk LV, Visser L, Diepstra A, Noordzij W, Williams SP, Ungewickell A, Elias SG, de Vries EGE, Niezink AGH, van Meerten T.   +18 more
europepmc   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source

Neuropsychiatric Tolerability of Long-Acting Cabotegravir and Rilpivirine in People With HIV With Prior INSTI-Related CNS Toxicity: A Real-World Cohort Study. [PDF]

Open Forum Infect Dis
Rosas Cancio-Suárez M, Moreno A, Terrón SDC, Vivancos MJ, Vélez Díaz-Pallarés M, Casado JL, Cano C, Navarro-Soler R, Moreno S, Pérez-Elías MJ.   +9 more
europepmc   +1 more source