Results 31 to 40 of about 291,366 (310)
Second-Line Treatment of Metastatic Renal Cell Carcinoma in the Era of Predictive Biomarkers
Diagnostics, 2023 Background: Over the past few years, significant advancements have been achieved in the front-line treatment of metastatic renal cell carcinomas (mRCCs).
Andreea Ioana Parosanu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Cardiovascular Mortality in Type 2 Diabetes Patients with Incident Exposure to Insulin Glargine
Journal of Diabetes Research, 2015 The study investigated the impact of insulin glargine exposure on cardiovascular mortality in type 2 diabetes patients with incident insulin initiation.
Sorin Ioacara +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Norbert Elias und das Janusgesicht der Staaten
, 2017 Norbert Elias im Interview mit Peter Ludes, Frank Adler und ...
Ludes, Peter, Elias, Norbert
core +1 more source
MedicinaCutaneous metastases from clear cell renal carcinoma (ccRC) are uncommon and often indicate a poor prognosis. These metastases typically occur on the scalp, face, and trunk, and they can be difficult to diagnose due to their resemblance to benign ...
Carmen Andrada Iliescu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Der graben um den altar des Elias
Estudios Eclesiásticos, 1960 La tradición dice que Elías cavó una zanja alrededor del altar en el monte Carmelo (1Re 18, 29-38). Esta hipótesis no ha sido del todo aceptada por la dificultad de sus explicaciones, tanto por la causa de la excavación, como por la talla que tendría. Se
Hubert Junker
doaj
LifeIatrogenic bile duct injury (IBDI) constitutes a major complication of cholecystectomy. The optimal timing, method, and setting for definitive repair remain subjects of debate.
Catalin Piriianu +5 more
doaj +1 more source