Results 91 to 100 of about 593,243 (307)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Plant Hormesis Management with Biostimulants of Biotic Origin in Agriculture

Frontiers in Plant Science, 2017
Over time plants developed complex mechanisms in order to adapt themselves to the environment. Plant innate immunity is one of the most important mechanisms for the environmental adaptation.
Marcela Vargas-Hernandez, Israel Macias-Bobadilla, Ramon G. Guevara-Gonzalez, Sergio de J. Romero-Gomez, Enrique Rico-Garcia, Rosalia V. Ocampo-Velazquez, Luz de L. Alvarez-Arquieta, Irineo Torres-Pacheco   +7 more
doaj   +1 more source

The role of respiratory burst oxidase homologues in elicitor-induced stomatal closure and hypersensitive response in Nicotiana benthamiana

Journal of Experimental Botany, 2009
Active oxygen species (AOS) are central components of the defence reactions of plants against pathogens. Plant respiratory burst oxidase homologues (RBOH) of gp91phox, a plasma membrane protein of the neutrophil nicotinamide adenine dinucleotide ...
Huajian Zhang, Q. Fang, Zhengguang Zhang, Yuanchao Wang, Xiaobo Zheng   +4 more
semanticscholar   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Plant improvement and metabolite production in Cannabis sativa: Recent biotechnological advances

Plant Trends
The Cannabis sativa plant is an excellent source of metabolites, fiber, and medicinal properties. Phytocannabinoids are the secondary metabolites naturally derived from Cannabis plant species.
S.M. Ahsan, Md. Injamum-Ul- Hoque, Ashim kumar, Shifa Shaffique, Md.Mezanur Rahman, Hyong Woo Choi   +5 more
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Etude des salives de pucerons : un préalable au développement de nouveaux bio-insecticides [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2010
Study of aphid saliva: a prerequisite to new bio-insecticides development. Aphids, major insect pests of forests, cereal, vegetable, fruit and ornamental crops, are controlled mainly by synthetic insecticides. However, due to the adverse effects of these
Harmel, N., Haubruge, E., Francis, F.
doaj  

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Understanding MeJA induced-resistance to Phytophthora cinnamomi in holm oak embryogenic lines

Frontiers in Plant Science
Holm oak (Quercus ilex L.) decline in Mediterranean forests is mostly driven by the synergistic effects of drought and Phytophthora cinnamomi, yet effective protection strategies remain elusive.
Marian Morcillo, Rosa Sanchez-Lucas, Ester Sales, Jesús Jorrín-Novo, Eva Miedes, Isabel Arrillaga   +5 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source