Results 231 to 240 of about 34,519 (263)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

Effect of Soil-Applied Metabolic Modulators on the Accumulation of Specialized Metabolites in <i>Chelidonium majus</i> L. [PDF]

open access: yesMolecules
Stasińska-Jakubas M   +5 more
europepmc   +1 more source

Hydrogen Peroxide-Oxidative Signaling Enhances Biosynthesis of Specialized Metabolites in <i>Baccharis conferta</i> Kunth. [PDF]

open access: yesInt J Mol Sci
Moreno-Anzúrez NE   +6 more
europepmc   +1 more source

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