Results 71 to 80 of about 19,305 (300)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Frontiers in Plant ScienceFeijoa (Acca sellowiana (O. Berg.) Burret), also known as pineapple guava, is a member of the Myrtaceae family and is well known for its fruit. Chemical profiling of the different tissues of the feijoa plant has shown that they generate an array of ...
Sanjeev V. Raikar +4 more
doaj +1 more source
Foods, 2019 The present study investigated the effects of jasmonic acid (JA), chitosan, and salicylic acid (SA) on the accumulation of phenolic compounds in germinated buckwheat.
Chang Ha Park +6 more
doaj +1 more source
Methods of Isolation and Characterization of Oligogalacturonide Elicitors
, 2017 Oligogalacturonides (OGs) are pectic fragments derived from the partial degradation of homogalacturonan in the plant cell wall and able to elicit plant defence responses. Recent methodological advances in the isolation of OGs from plant tissues and their characterization have confirmed their role as bona fide plant Damage-Associated Molecular Patterns.
Benedetti, Manuel +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Putative elicitors used in this study.
, 2015 *Maximum dose per plant was calculated by dividing total amount of elicitor in mixture by the number of plants treated per application (10 for maize, cotton, and soybean). For rice, maximum dose per plant was lower because there were 10–15 plants per pot.
Jeffrey A. Davis (791261) +4 more
core +1 more source
Effectiveness of different elicitors in inducing resistance in chilli (Capsicum annuum L.) against pathogen infection. [PDF]
, 2013 The excessive application of pesticides for agricultural production in Malaysia has raised quite some concern about environmental safety and sustainability.
Berahim, Zulkarami +4 more
core +1 more source
Chemical Elicitors of Antibiotic Biosynthesis in Actinomycetes [PDF]
Microorganisms, 2018 Whole genome sequencing of actinomycetes has uncovered a new immense realm of microbial chemistry and biology. Most biosynthetic gene clusters present in genomes were found to remain “silent” under standard cultivation conditions. Some small molecules—chemical elicitors—can be used to induce the biosynthesis of antibiotics in actinobacteria and to ...
Anton P. Tyurin +2 more
openaire +3 more sources