Results 111 to 120 of about 1,815,125 (304)

New standards in HER2-low testing: the CASI-01 comparative methods studyResearch in context

EBioMedicine
Summary: Background: The introduction of Trastuzumab deruxtecan (T-Dxd) has exposed clinically significant limitations in accurately detecting HER2-low expression testing when using immunohistochemistry (IHC) assays originally developed to detect HER2 ...
David J. Dabbs, Emina Torlakovic, Søren Nielsen, Suzanne C. Parry, Jing Yu, Catherine Stoos, Beth Clark, Henrik Høeg, Jeppe Thagaard, Seshi R. Sompuram, Stephen P. Naber, Yukako Yagi, James Sayre, Kodela Vani, Mélissande Cossutta, Francoise Soussaline, Alexandre Papine, Nils A. t'Hart, Matthias J. Szabolcs, Bharat Jasani, Mary Kinloch, Luis Chiriboga, Keith Miller, Steve Bogen   +23 more
doaj   +1 more source

A "New" Strategy for Afghanistan and Its Region

, 2009
The report assesses the strategy of the Obama Administration as stated in early 2009 toward Afghanistan and provides recommendations for Afghanistan and its region. This strategy resembles a strategic framework more than a specific strategy.
Liechtenstein Institute on Self-Determination
core  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

A New Vision for Afghanistan

, 2008
The report assesses progress made and addresses critical issues facing Afghanistan in the areas of security, regional relations, elections, governance and rule of law, the economy and human development, and policy in the region and macro region.
Liechtenstein Institute on Self-Determination
core  

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Data mining-based decision support system for educational decision makers: Extracting rules to enhance academic efficiency

Computers and Education: Artificial Intelligence
The exponential growth of data in the field of education has created a pressing demand for a robust system capable of analyzing this vast amount of information, empowering decision-makers to enhance academic efficiency.
Shima Maniyan, Rouzbeh Ghousi, Abdorrahman Haeri   +2 more
doaj   +1 more source

Determinants of outcome in patients eligible for thrombolysis for ischemic stroke.

Vascular health and risk management, 2007
Objectives: Eligibility criteria for thrombolysis in ischemic stroke have been clearly defined. However, not all eligible patients benefit from this treatment. This study aimed to assess the determinants for clinical outcome in consecutive, eligible patients with ischemic stroke treated with thrombolysis in a single-center study.
CASO, Valeria, PACIARONI, Maurizio, Venti M, Palmerini F, Silvestrelli G, Milia P, Biagini S, AGNELLI, Giancarlo   +7 more
openaire   +3 more sources

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Evaluation of postoperative pain associated with different working length determination methods: a randomised clinical study

BMC Oral Health
Background Postoperative pain is a common concern in endodontic treatment. In teeth with asymptomatic irreversible pulpitis, accurate working length determination is critical for effective root canal therapy and may influence postoperative discomfort ...
Gamze Nalci Calik, Betül Aycan Alim Uysal, Fatma Begüm Peker, Mehmet Burak Guneser   +3 more
doaj   +1 more source