Transmissible gastroenteritis virus: Identification of M protein-binding peptide ligands with antiviral and diagnostic potential [PDF]
, 2013 The membrane (M) protein is one of the major structural proteins of coronavirus particles. In this study, the M protein of transmissible gastroenteritis virus (TGEV) was used to biopan a 12-mer phage display random peptide library.
Ren, Xiaofeng +4 more
core +1 more source
Diagnostic Accuracy of Five Serologic Tests for Strongyloides stercoralis Infection [PDF]
, 2014 Background:The diagnosis of Strongyloides stercoralis (S. stercoralis) infection is hampered by the suboptimal sensitivity of fecal-based tests. Serological methods are believed to be more sensitive, although assessing their accuracy is difficult because
Albonico, Marco +12 more
core +3 more sources
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
28 kDa FASCIOLA GIGANTICA CYSTEINE PROTEINASE (FgCL3) BASED SERO-DIAGNOSIS OF BOVINE TROPICAL FASCIOLOSIS IN THE DAIRY ANIMALS OF PUNJAB, INDIA [PDF]
Exploratory Animal and Medical ResearchTropical fasciolosis is one of the neglected diseases affecting a large proportion of dairy animals in developing countries like India and its economic assessment has revealed huge production losses in affected animals.
Abhishek Gupta +3 more
doaj +1 more source
Comparisons of ELISA and Western blot assays for detection of autophagy flux [PDF]
, 2017 We analyzed autophagy/mitophagy flux in vitro (C2C12 myotubes) and in vivo (mouse skeletal muscle) following the treatments of autophagy inducers (starvation, rapamycin) and a mitophagy inducer (carbonyl cyanide m-chlorophenylhydrazone, CCCP) using two ...
Choi, Yong-bok +4 more
core +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Serological and Molecular Identification of Brucella spp. in Pigs from Cairo and Giza Governorates, Egypt [PDF]
, 2019 Brucellosis is considered as endemic disease of animals and humans since thousands of years in Egypt. However, brucellosis in pigs has never been reported in Egypt.
El-Adawy, Hosny +8 more
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Quantum Mechanics, Fields, Black Holes, and Ontological Plurality
PhilosophiesThe ontology behind quantum mechanics has been the subject of endless debate since the theory was formulated some 100 years ago. It has been suggested, at one time or another, that the objects described by the theory may be individual particles, waves ...
Gustavo E. Romero
doaj +1 more source
A new proof of the Alexander-Hirschowitz interpolation Theorem
, 2010 The classical polynomial interpolation problem in several variables can be generalized to the case of points with greater multiplicities. What is known, as yet, is essentially concentrated in the Alexander-Hirschowitz Theorem which says that a general ...
Postinghel, Elisa
core +1 more source