Results 261 to 270 of about 1,280,636 (346)

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

Future flooding tolerant rice germplasm: Resilience afforded beyond Sub1A gene. [PDF]

open access: yesPlant Genome
Anumalla M   +38 more
europepmc   +1 more source

METABOLIC EFFICIENCY IN ELITE AMENORRHEIC AND EUMENORRHEIC MIDDLE-DISTANCE AND DISTANCE RUNNERS

open access: bronze, 1980
Jack H. Wilmore   +7 more
openalex   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

open access: yesAdvanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao   +9 more
wiley   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen   +13 more
wiley   +1 more source

Aerobic and Anaerobic Metabolism During Monofin Swimming in Trained Breath-Hold Divers. [PDF]

open access: yesJ Funct Morphol Kinesiol
Drviš I   +4 more
europepmc   +1 more source

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