Results 291 to 300 of about 1,280,636 (346)

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Characteristics of Japanese Elite Athletes Who Utilized Mental Health Services at the Japan High Performance Sports Center During the Tokyo 2020 Olympics and the COVID-19 Pandemic. [PDF]

Cureus
Hashimoto R, Yamaguchi T, Suzuki K, Sekiguchi K, Tanaka M, Eda K, Tomori A, Kamahara K, Dohi M, Machidori K, Nakajima K.   +10 more
europepmc   +1 more source

SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40

Advanced Science, EarlyView.
SUMOylation regulates mitochondrial processes, but its impact on protein import remains unclear. TOM40 is identified, a mitochondrial outer membrane channel protein, as a substrate of deSUMOylase SENP6. TOM40 SUMOylation disrupts outer membrane complex assembly, inhibits protein import, and compromises mitochondrial homeostasis.
Liubing Hu, Jianshuang Li, Haolin Guo, Lei Su, Peina Dong, Juan Huang, Yanyan Liu, Xinjie Liu, Zhenhuan Luo, Wei Xiong, Zhenyu Ju, Qinghua Zhou, Hao Wang, Wenjun Wang   +13 more
wiley   +1 more source

The Effect of Perceptual-Cognitive Skills in College Elite Athletes: An Analysis of Differences Across Competitive Levels. [PDF]

Sports (Basel)
Wu KC, Lin HC, Cheng ZY, Chang CH, Chang JN, Tai HL, Liu SI.   +6 more
europepmc   +1 more source

Ferrocene‐Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques

Advanced Science, EarlyView.
Aminoferrocene is employed to modify black phosphorus, generating stable phosphorus radicals (FcP). The FcP is then functionalized with hyaluronic acid (HA) to produce the HA‐FcP radical complex, thereby developing a novel, highly efficient, sensitive, long‐lasting, and low‐heavy‐metal‐content radical contrast agent for targeted imaging of ...
Xiao Huang, Yuanyuan Zhao, Miao Zhou, Yukang Guo, Haiyun Wang, Yuanyuan Chen, Jian Peng   +6 more
wiley   +1 more source

Comparative Evaluation of Push-Out Bond Strength at Various Levels for Two Different Size Radicular Posts Cemented with Two Different Resin Cements: An <i>In vitro</i> Study.

J Pharm Bioallied Sci
Vijaykumar N, Haseeb SA, Chandrashekar Rao VK, Akashata KR, Swamy MC, Reddy MK.   +5 more
europepmc   +1 more source

Adaptation and psychometric properties of Psychological Skills Inventory for Sport (PSIS-R5) in Latvian athletes: Insights and implications for practice. [PDF]

PLoS One
Volgemute K, Ulme G, Perepjolkina V, Licis R, Abele A, Lavins R, Klonova A, Tihija A, Grants E.   +8 more
europepmc   +1 more source

A Dynamic Contrast‐Enhanced MRI‐Based Vision Transformer Model for Distinguishing HER2‐Zero, ‐Low, and ‐Positive Expression in Breast Cancer and Exploring Model Interpretability

Advanced Science, EarlyView.
This study develops a Vision Transformer‐based DCE‐MRI model for the non‐invasive classification of HER2 expression in breast cancer, demonstrating robust performance across multicenter cohorts. By integrating transcriptomic analysis, the model reveals immune‐related pathway differences among distinct HER2 expression levels.
Xu Zhang, Yi‐Yuan Shen, Guan‐Hua Su, Yuan Guo, Ren‐Cheng Zheng, Si‐Yao Du, Si‐Yi Chen, Yi Xiao, Zhi‐Ming Shao, Li‐Na Zhang, He Wang, Yi‐Zhou Jiang, Ya‐Jia Gu, Chao You   +13 more
wiley   +1 more source

A psychometric study of the team psychological safety scale and sport psychological safety inventory in Swedish elite sports. [PDF]

Sci Rep
Lundqvist C, Bermon S, Timpka T.
europepmc   +1 more source

The Face of the Elite

, 2000
openaire   +3 more sources