Archaeogenetics reconstructs demography and extreme parental consanguinity in a Bronze Age community from Southern Italy. [PDF]
Fontani F +14 more
europepmc +1 more source
Extremity Function After Transfemoral Transcatheter Aortic Valve Implantation: A TAVI XS Sub‐Study
ABSTRACT Background Physical decline after transcatheter aortic valve implantation (TAVI) is associated with worse outcomes. However, data on post‐TAVI extremity function are limited. This sub‐study of the TAVI XS trial aimed to assess extremity function after transfemoral TAVI, evaluate functional decline, compare outcomes between upper‐and lower ...
Geert A. A. Versteeg +20 more
wiley +1 more source
North Pontic crossroads: Mobility in Ukraine from the Bronze Age to the early modern period [PDF]
Saag L +38 more
europepmc +2 more sources
An expansive global oxygenation of Earth's surface environments 1.4 billion years ago. [PDF]
Yan H +13 more
europepmc +1 more source
Clinical Impact of Angiographic Complications Occurring During Percutaneous Coronary Interventions
ABSTRACT Background The clinical impact of different types of angiographic complications during elective PCIs remains largely unexplored. Aims To explore the incidence, management, and outcomes of angiographic complications by type and severity during non‐urgent, non‐CTO PCIs. Methods Clinical and procedural characteristics were prospectively collected
Emiliano Bianchini +16 more
wiley +1 more source
Ancient DNA reveals a two-clanned matrilineal community in Neolithic China. [PDF]
Wang J +27 more
europepmc +1 more source
Burial mounds of Scythian elites in the Eurasian steppe: New discoveries
openaire +1 more source
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
Ancient genomes reveal the genetic structure and population interaction in the Central Plains of China during the Eastern Zhou Period. [PDF]
Wu X +11 more
europepmc +1 more source
Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu +8 more
wiley +1 more source

