Results 71 to 80 of about 1,086 (251)

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

Kinship practices at the early bronze age site of Leubingen in Central Germany

open access: yesScientific Reports
With the beginning of the Early Bronze Age in Central Europe ~ 2200 BC, a regional and supra-regional hierarchical social organization emerged with few individuals in positions of power (chiefs), set apart by rich graves with extensive burial ...
Sandra Penske   +7 more
doaj   +1 more source

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu   +10 more
wiley   +1 more source

Photoelectric‐Coupled Ferroelectric Heterojunctions for Ultrahigh NO2 Sensing With Polarization‐Memory‐Assisted Interfacial Modulation

open access: yesAdvanced Science, EarlyView.
This study demonstrates a Bi2WO6/SrBi2Ta2O9 heterojunction where light‐driven ferroelectric polarization reversal couples with persistent photoconductivity, enabling exclusive NO2 selective room‐temperature sensing. The device achieves a two‐order‐of‐magnitude sensitivity enhancement over an unpolarized device, a sub‐ppb detection limit, and robust ...
Liping Tan   +11 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

On the edge of the eurasian steppes: the sarmatian culture in the 1st–3rd centuries ad east of the Carpathians

open access: yesПоволжская археология
The paper analyses the Sarmatian culture east of the Carpathians during the 1st-3rd centuries AD, shedding light on their burial practices, artefacts, and socio-economic interactions.
Grumeza Lavinia, Cojocaru Victor
doaj   +1 more source

Elite Burials of the Han Period at Xiaobaozi (Shaanxi, China)

open access: yesProblems of Archaeology, Ethnography, Anthropology of Siberia and Neighboring Territories
This article overviews the main Internet resources on the excavations of the elite burials at the Xiaobaozi burial ground (Shaanxi Province) of the Western Han period, which were done in 2024. Online publications play an important role in the initial processing of the collected evidence and promoting this archaeological discovery to the wider public ...
openaire   +1 more source

Bruce Wannell, Wahid Amini. Herat Elite Burials. An endangered heritage. [PDF]

open access: yesAbstracta Iranica, 2016
Ce livre propose un catalogue de tombes en pierre sculptee (steles ou cenotaphes) a decor epigraphique conservees a Herat. Ce recensement est le resultat d’une etude menee entre 2007 et 2008 par des architectes sous l’egide de l’Aga Khan Trust for Culture : il s’agissait alors d’enregistrer les tombes conservees dans la cour principale du mausolee ...
openaire   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

open access: yesAdvanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen   +6 more
wiley   +1 more source

Classification of burial rituals of the cemeteries without burial mounds in regions of the Tsarevskoe ancient settlement

open access: yesПоволжская археология, 2015
Article is dedicated to analysis of burial rituals of the Golden Horde cemeteries without burial mounds in surroundings of the Tsarevskoe ancient settlement.
Nedashkovsky Leonard F.
doaj  

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