Results 91 to 100 of about 30,633 (317)

Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu, Yin Zi‐Xiao, Chen Ying‐Chuan, Timon Merk, Thomas Binns, Ma Ruo‐Yu, Du Ting‐Ting, Liu Yu‐Ye, Xie Hu‐Tao, Shi Lin, Yang An‐Chao, Meng Fan‐Gang, Wolf‐Julian Neumann, Andrea A. Kühn, Zhang Jian‐Guo   +14 more
wiley   +1 more source

National Institute of Health and Care Excellence Clinical Criteria for the Diagnosis of Knee Osteoarthritis: A Prospective Diagnostic Accuracy Study in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King, Ian Stanaitis, Vivian Hung, Sahil Koppikar, Esther J. Waugh, Lorraine Lipscombe, Gillian A. Hawker   +6 more
wiley   +1 more source

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

Arthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner, Anna Shmagel, Gerd Horneff, Ivan Foeldvari, Jordi Antón, Athimalaipet V. Ramanan, Yuli Qian, Kristina Unnebrink, Shuai Hao, Heidi S. Camp, Nasser Khan, Wei Liu, Mohamed‐Eslam F. Mohamed   +12 more
wiley   +1 more source

Incidence of Side Effects Associated With Acetaminophen in People Aged 65 Years or More: A Prospective Cohort Study Using Data From the Clinical Practice Research Datalink

Arthritis Care &Research, EarlyView.
Objective The main objective of this study is to examine the safety of oral acetaminophen at its therapeutic dose in adults aged ≥65 years. Methods This population‐based cohort study used the Clinical Practice Research Datalink‐Gold data. Participants were aged ≥65 years registered with a UK general practice for at least 12 months between 1998 and 2018.
Jaspreet Kaur, Georgina Nakafero, Abhishek Abhishek, Christian Mallen, Michael Doherty, Weiya Zhang   +5 more
wiley   +1 more source

“It's Just Good Science”: A Qualitative Study Exploring Equity, Diversity, and Inclusion in Canadian Arthritis Research

Arthritis Care &Research, EarlyView.
Objective Despite knowledge that health outcomes vary according to patient characteristics, identity, and geography, including underrepresented populations in arthritis research remains a challenge. We conducted interviews to explore how researchers in arthritis have used equity, diversity, and inclusion (EDI) principles to inform their research ...
Megan M. Thomas, Mark Harrison, Cheryl Barnabe, Charlene E. Ronquillo, J. Antonio Avina‐Zubieta, Anna Samson, Michael Kuluva, Natasha Trehan, Mary A. De Vera   +8 more
wiley   +1 more source

Estimating Budget Impact and Joint Replacement Avoidance by Implementing a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis in a Publicly Insured Health Care System

Arthritis Care &Research, EarlyView.
Objective The study objective was to estimate the budget impact of funding a standardized education and exercise therapy program, Good Life with osteoArthritis in Denmark (GLA:D) for people with hip and knee osteoarthritis (OA) waiting for total joint replacement (TJR) consultation in a universal publicly insured health care system in Canada.
Darren R. Mazzei, Jackie L. Whittaker, Peter Faris, Tracy Wasylak, Deborah A. Marshall   +4 more
wiley   +1 more source

Technology Innovation and Guardrails in Elite Sport: The Future is Now. [PDF]

Sports Med, 2023
Guppy F, Muniz-Pardos B, Angeloudis K, Grivas GV, Pitsiladis A, Bundy R, Zelenkova I, Tanisawa K, Akiyama H, Keramitsoglou I, Miller M, Knopp M, Schweizer F, Luckfiel T, Ruiz D, Racinais S, Pitsiladis Y.   +16 more
europepmc   +1 more source

Priority Musculoskeletal Health Research Questions for People With Generalized Joint Hypermobility: An International Delphi Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to identify the top 10 international research priorities for musculoskeletal health of people with generalized joint hypermobility. Methods A three‐round Delphi method using an online survey was implemented. Three participant stakeholder groups were eligible for inclusion: (1) people with lived experience of joint ...
Sara Habibian, Verity Pacey, Cliffton Chan, Alan J. Hakim, Cylie M. Williams   +4 more
wiley   +1 more source

A biomechanical comparison of concussion and head acceleration events in elite-level American football and rugby union [PDF]

arXiv
Elite-level American football and rugby union are two high-contact sports with growing clinical and legal concerns over player safety, necessitating a comparative analysis. A biomechanical comparison of concussion and head acceleration events (HAEs) in elite-level American football and rugby union was undertaken.
arxiv  

Pregnancy Outcomes of Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review

Arthritis Care &Research, EarlyView.
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng, Neda Amiri, Vicki Cheng, Ursula Ellis, Jacquelyn J. Cragg, Mark Harrison, Laurie Proulx, Mary A. De Vera   +7 more
wiley   +1 more source