Results 281 to 290 of about 591,798 (358)

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Correction: Hormonal Neuroendocrine and Vasoconstrictor Peptide Responses of Ball Game and Cyclic Sport Elite Athletes by Treadmill Test

, 2016
Anna Protzner, Márta Szmodis, Anna Udvardy, Edit Bosnyák, Emese Trájer, Zsolt Komka, István Györe, Miklós Tóth   +7 more
openalex   +2 more sources

Elasticity‐Driven Nanomechanical Interaction to Improve the Targeting Ability of Lipid Nanoparticles in the Malignant Tumor Microenvironment

Advanced Science, EarlyView.
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee, Loi Nguyen Dang, Jinsol Choi, Haesoo Kim, Lyndon Bastatas, Soyeun Park   +5 more
wiley   +1 more source

CXCL6 Reshapes Lipid Metabolism and Induces Neutrophil Extracellular Trap Formation in Cholangiocarcinoma Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He, Zi‐Yi Wang, Bin Xu, Cheng‐Jie Zhong, Lu‐Na Wang, Huan‐Chen Shi, Zi‐Yue Yang, Shi‐Qi Zhou, Hui Li, Bo Hu, Xiao‐Dong Zhu, Ying‐Hao Shen, Jian Zhou, Jia Fan, Hui‐Chuan Sun, Cheng Huang   +15 more
wiley   +1 more source

Recurrent and Subsequent Injuries in Professional and Elite Sport: a Systematic Review. [PDF]

Sports Med Open, 2020
Bitchell CL, Varley-Campbell J, Robinson G, Stiles V, Mathema P, Moore IS.   +5 more
europepmc   +1 more source

Influence of Strength and Power Capacity on Change of Direction Speed and Deficit in Elite Team-Sport Athletes [PDF]

, 2019
Tomás T. Freitas, Lucas A. Pereira, Pedro E. Alcaráz, Ademir Felipe Schultz de Arruda, Aristide Guerriero, Paulo Henrique Silva Marques de Azevedo, Irineu Loturco   +6 more
openalex   +1 more source

Achromatic 3D Multi‐Color Orbital Angular Momentum Holography

Advanced Science, EarlyView.
This work presents an achromatic 3D multicolor orbital angular momentum (OAM) holography based on spatial multiplexing. By integrating wavelength‐specific lens functions onto monochromatic Fourier OAM‐dependent holograms and high‐resolution spatial discretization and interleaving via two‐photon lithography (TPL), the approach addresses axial chromatic ...
Hang Su, Baoli Li, Yike Bai, Yiqi Ye, Yibo Dong, Xinyuan Fang   +5 more
wiley   +1 more source

The future of dispute resolution in international trade

Applied Economic Perspectives and Policy, EarlyView.
Abstract Given ongoing dysfunction of the World Trade Organization's Appellate Body, the focus of this article is on the future of trade dispute resolution, with evaluation of two questions: (i) What is the current status of WTO dispute resolution as compared to that conducted through existing preferential trade agreements (PTAs)? and (ii) What are the
Ian Sheldon, Daniel C. K. Chow
wiley   +1 more source

What matters for agricultural trade? Assessing the role of trade deal provisions using machine learning

Applied Economic Perspectives and Policy, EarlyView.
Abstract This paper employs machine learning to determine which preferential trade agreement (PTA) provisions are relevant to agricultural trade patterns and the factors that may influence their adoption. Utilizing the three‐way gravity model, we apply plug‐in Lasso regularized regression to pinpoint predictive PTA provisions for agricultural trade ...
Stepan Gordeev, Jeremy Jelliffe, Dongin Kim, Sandro Steinbach   +3 more
wiley   +1 more source