Results 221 to 230 of about 65,019 (298)

Cost Utility Analysis of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation for Chronic Rhinosinusitis With Nasal Polyps

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is managed after sinus surgery with topical corticosteroids. Given limited distribution of nasal steroid sprays, patients have the option of either steroid nasal irrigation (SNI) or exhalation delivery system with fluticasone (EDS‐FLU).
Daniel Xiao   +3 more
wiley   +1 more source

DNA‐mimic for Specific Surface Functionalization of Zr‐MOFs for Bacterial Targeting

open access: yesAngewandte Chemie, EarlyView.
We introduce phosphotyrosine‐modified PNA as a superior, single‐step post‐synthesis surface coating for PCN‐222. The DNA mimic allows for controlled post‐functionalization with single‐stranded DNA for the attachment of protein moieties for bacterial targeting. ABSTRACT Nanosized metal–organic frameworks (MOFs) are versatile platforms used in biomedical
Anna Scheeder   +9 more
wiley   +2 more sources

Partial hearing recovery after cochlear nerve surface transplantation of hair follicle‐derived neural crest stem cells in neural hearing loss rat

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study comprises three experimental parts. Part 1. Time‐course of ouabain‐induced hearing loss. Rats received ouabain (10 mM) via round window application. ABR/DPOAE tests and histological analyses were performed at 2, 7, and 30 days post‐treatment to characterize SGN and glial cell degeneration. Part 2.
Huidong Chen   +9 more
wiley   +1 more source

Ketal Protection of Glycerol for Selective Electrosynthesis of Glyceric Acid in Highly Alkaline Media

open access: yesAngewandte Chemie, EarlyView.
Using a ketal‐protected glycerol derivative (solketal) as the oxidation substrate enables site‐selective electrooxidation that suppresses C–C cleavage on non‐noble catalysts. Highly alkaline conditions promote reactive solketal alkoxide formation, weaken the Cα─H bond to facilitate dehydrogenation, and buffer local acidification, enabling a record‐high
Jiamin Wang   +6 more
wiley   +2 more sources

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang   +45 more
wiley   +1 more source

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

open access: yesAngewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans   +10 more
wiley   +2 more sources

Direct evidence for magnetohydrodynamic disk winds driving rotating outflows in protostar HOPS 358. [PDF]

open access: yesNat Commun
Kim CH   +6 more
europepmc   +1 more source

Design Guidelines for Anode Modifications to Eliminate Soft Short Circuits in Anode‐Free Na Batteries Under High Current Density With Large‐Capacity Plating, Demonstrated via Initiated Chemical Vapor Deposition (iCVD)

open access: yesAngewandte Chemie, EarlyView.
This work establishes a laterally homogeneous organic–inorganic hybrid interphase for soft‐short‐free anode‐free sodium metal batteries under extended cycling at high current density and high plating capacity. In contrast to conventional strategies that evolve into laterally heterogeneous interphases and induce localized Na filament growth, the pDFHA ...
Yeongjun Oh   +7 more
wiley   +2 more sources

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