Results 31 to 40 of about 54,387 (315)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

APPLICATION OF ASYMMETRIC PROFILE IN GEARINGS WITH ECCENTRIC GEARS [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2014
Gearing was designed to meet specific requirement, during one rotation was continuous change of gear ratio. The gearing consists of two identical gears. The basic shape of the wheel is formed by an ellipse.
Silvia MEDVECKÁ-BEŇOVÁ   +1 more
doaj  

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

ASPECTS AND GEOMETRIC INTERPRETATION IN SOLVING CONICAL SECTIONS

open access: yesJournal of Industrial Design and Engineering Graphics, 2019
In mathematics, a conic is the curve that is obtained by intersecting a plane with a cone. Is well known that the shape of this curve may differ quite a bit depending on the position of the intersection plane relative to the cone axis, as it is actually ...
Alina DUTA   +4 more
doaj   +4 more sources

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

On the Images of Ellipses Under Similarities

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
We consider ellipses corresponding to any norm function on the complex plane and determine their images under the similarities which are special Möbius transformations.
Özgür Nihal Yilmaz
doaj   +1 more source

Numerical Calculation of Area of Elliptical Segments

open access: yesMathematics, 2020
In this paper, we introduce the notion of an elliptical segment as some analogy of the circular segment and we focus on the problem of calculation of its area.
Dusan Vallo   +2 more
doaj   +1 more source

Covering with Ellipses

open access: yesAlgorithmica, 2003
We address the problem of how to cover a set of "required points" by a small number of "axis-parallel ellipses" that avoid a second set of "forbidden points". We study geometric properties of such covers and present an efficient randomized approximation algorithm for the cover construction.
Efrat, Alon   +5 more
openaire   +2 more sources

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

open access: yesAdvanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat   +6 more
wiley   +1 more source

Sebuah Telaah Elips dan Lingkaran Melalui Sebuah Pendekatan Aljabar Matriks

open access: yesCauchy: Jurnal Matematika Murni dan Aplikasi, 2010
In this article, ellipse and circle will be learnt in depth via matrix algebra approach. The discussion of the both is started from their classic definition continued by surveying ellipse in matrix form.
Rahmat Sagara
doaj   +1 more source

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