Results 131 to 140 of about 110,736 (292)

锥椭球反光镜加工与检测原理与应用

open access: yesJixie chuandong, 2011
Surfaces shaped by conic sections are widely applied in engineering practice.Grinding machining based on custom macro B is proposed to improve efficiency and accuracy of taper ellipsoid manufacturing.The tool moves exactly according to the section ...
赵文辉, 段振云, 何龙, 任仲伟
doaj  

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter   +5 more
wiley   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel   +13 more
wiley   +1 more source

Ellipsoid Methods for Metric Entropy Computation

open access: yes
We present a new methodology for the characterization of the metric entropy of infinite-dimensional ellipsoids with exponentially decaying semi-axes. This procedure does not rely on the explicit construction of coverings or packings and provides a unified framework for the derivation of the metric entropy of a wide variety of analytic function classes,
Allard, Thomas, Bölcskei, Helmut
openaire   +2 more sources

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao   +20 more
wiley   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

open access: yesAdvanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan   +8 more
wiley   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

open access: yesAdvanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns   +10 more
wiley   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel   +6 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

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