Advanced Science, EarlyView.Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source
A Comparative Study and Introduction of a New Heat Source Model for the Macro-Scale Numerical Simulation of Selective Laser Melting Technology. [PDF]
Materials (Basel)Zhang H, Wang S, Wang J, Yan Z.
europepmc +1 more source
Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications
Advanced Science, EarlyView.Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo +12 more
wiley +1 more source
Tailor-Made Vessels for Enhancing the Mechanochemical Energy Transfer and Milling Efficiency. [PDF]
ChemSusChemJansen T, Thomas LC, Bolm C.
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Mechanochemical feedback between confinement and actin crosslinking drives the shape dynamics of liquid-like droplets. [PDF]
Nat CommunMansour D +7 more
europepmc +1 more source
The ellipsoid method in linear programming
Advances in Applied Mathematics, 1980 openaire +2 more sources
Electronic Structure Reorganization in MPS3 via d‐Shell‐Selective Alkali Metal Doping
Advanced Science, EarlyView.Alkali metal doping of layered MPS3 antiferromagnets reveals d‐shell‐selective responses. While MnPS3 resists charge transfer due to its half‐filled 3d5 shell, FePS3 and NiPS3 behave similarly to CoPS3 by accommodating extra d‐electrons. Yet only CoPS3, with its least stable d‐shell, undergoes pronounced band restructuring and a semiconducting‐to ...
Jonah Elias Nitschke +12 more
wiley +1 more source
Research on the Loran-C Pseudorange Positioning Method Based on an Ellipsoidal Geodesic Model and Its Application in Inland Areas. [PDF]
Sensors (Basel)Gao A +6 more
europepmc +1 more source
Advanced Science, EarlyView.A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source