Results 61 to 70 of about 110,756 (290)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Advances in Mechanical Engineering, 2013 We developed a new immersed boundary method which has various advantages, such as accuracy, flexibility, and rapidness combining with the level set method.
Atsuki Iijima +2 more
doaj +1 more source
Stochastic Ellipsoid Methods with Multiple Cuts
Transactions of the Institute of Systems, Control and Information Engineers, 2008 Robust control systems synthesis is generally recast as a class of robust feasibility problems which is to find a solution satisfying a set of parameter-dependent convex constraints for all possible parameter values. For this class of the problems, a stochastic ellipsoid method with multiple cuts each of which corresponds to each of the constraint is ...
Takayuki Wada, Yasumasa Fujisaki
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Non-contrast low-dose CT can be used for volumetry of ADPKD
BMC Nephrology, 2023 Background Kidney volume provides important information for the diagnosis and prognosis of autosomal dominant polycystic kidney disease (ADPKD), as well as for the evaluation of the effects of drugs such as tolvaptan. Non-contrast computed tomography (CT)
Jaeyeong Yoo +8 more
doaj +1 more source
Shaped extensions of singular spectrum analysis [PDF]
, 2014 Extensions of singular spectrum analysis (SSA) for processing of non-rectangular images and time series with gaps are considered. A circular version is suggested, which allows application of the method to the data given on a circle or on a cylinder, e.g.
Golyandina, Nina, Shlemov, Alex
core
The boundary element approach to Van der Waals interactions
, 2007 We develop a boundary element method to calculate Van der Waals interactions for systems composed of domains of spatially constant dielectric response.
Balian +14 more
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
International Journal of Advanced Robotic Systems, 2017 A grasp planning method based on the volume and flattening of a generalized force ellipsoid is proposed to improve the grasping ability of a dexterous robotic hand. First, according to the general solution of joint torques for a dexterous robotic hand, a
Peng Jia +3 more
doaj +1 more source