Advanced Science, EarlyView.Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen +8 more
wiley +1 more source
Soliton dynamics and stability analysis of a double-chain DNA model with various chaos detection tools. [PDF]
Sci RepUllah MS, Akter R.
europepmc +1 more source
Subvoxel Control of Fiber Orientation via Multidirectional Shearing in 3D Printing
Advanced Science, EarlyView.A novel 3D printing technique enables subvoxel control of fiber orientation in all three directions through multidirectional shearing using nozzle rotation and inclination. It allows localized and tunable mechanical and thermal responses through programmable microstructures within a strand.
Berin Šeta +5 more
wiley +1 more source
Advanced fractional soliton solutions of the Joseph-Egri equation via Tanh-Coth and Jacobi function methods. [PDF]
Sci RepShakeel K +6 more
europepmc +1 more source
An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring
Advanced Science, EarlyView.Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar +6 more
wiley +1 more source
Constructing optical soliton wave structure and modulation instability analysis for coupled fractional Lakshmanan-Porsezian-Daniel equation with Kerr's law nonlinearity. [PDF]
Sci RepAghazadeh A, Lakestani M.
europepmc +1 more source
Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance
Advanced Science, EarlyView.By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam +6 more
wiley +1 more source
A new hybrid block collocation method for solving elliptic PDEs. [PDF]
Sci RepRufai MA +3 more
europepmc +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Soliton dynamics of the fourth-order nonlinear Boussinesq equation arising in shallow-water via advanced analytical techniques. [PDF]
Sci RepMalik S +3 more
europepmc +1 more source