Results 111 to 120 of about 3,531,269 (377)

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

open access: yesAdvanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang   +7 more
wiley   +1 more source

Lipschitz estimate for elliptic equations with oscillatory coefficients

open access: yesAIMS Mathematics
Regularity for elliptic equations with oscillatory coefficients was concerned. Problem domains were periodic and consisted of a connected region with normal permeability and a disconnected matrix block subset with high permeability.
Li-Ming Yeh
doaj   +1 more source

Degenerate Differential Operators with Parameters

open access: yesAbstract and Applied Analysis, 2007
The nonlocal boundary value problems for regular degenerate differential-operator equations with the parameter are studied. The principal parts of the appropriate generated differential operators are non-self-adjoint.
Veli B. Shakhmurov
doaj   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

Solvability of quasilinear elliptic equations with strong dependence on the gradient

open access: yesAbstract and Applied Analysis, 2000
We study the problem of existence of positive, spherically symmetric strong solutions of quasilinear elliptic equations involving p-Laplacian in the ball. We allow simultaneous strong dependence of the right-hand side on both the unknown function and its
Darko Žubrinić
doaj   +1 more source

Inverse problems for elliptic equations with power type nonlinearities [PDF]

open access: yesJournal des Mathématiques Pures et Appliquées, 2019
M. Lassas   +3 more
semanticscholar   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

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