Results 131 to 140 of about 3,272 (265)

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Periodic structures of solitons and shock wave solutions in the fractional nonlinear Shynaray-IIA equation via a generalized analytical method. [PDF]

Sci Rep
Iqbal M, Khan MI, Alrashdi HD, Algethamie R, Alomari FAH, Aljohani A, Mohammad N, Aljawi S.   +7 more
europepmc   +1 more source

Elliptic regularity and solvability for partial differential equations with Colombeau coefficients [PDF]

, 2003
Guenther Hoermann, Michael Oberguggenberger   +1 more
openalex   +1 more source

Transient Antiskyrmion‐Mediated Topological Transitions in Isotropic Magnets

Advanced Science, EarlyView.
A transient antiskyrmion‐mediated pathway that drives repeated stripe‐to‐skyrmion transitions is revealed, producing a net increase in topological charge in isotropic Dzyaloshinskii–Moriya interaction films. Experiments and simulations identify the antiskyrmion as a metastable excitation, enabling stochastic bitstream generation for probabilistic ...
Bingqian Dai, Tianyi Wang, Albert Lee, Shijie Xu, Zhongjian Bian, Xinyue Zhu, Puyang Huang, Aadi Chaturvedi, Yaochen Li, Yang Cheng, Qingyuan Shu, Haoran He, Hanshen Huang, Lixuan Tai, Kin Wong, Jinbo Yang, Anjan Soumyanarayanan, Zhaochu Luo, Kang L. Wang   +18 more
wiley   +1 more source

Constructing optical soliton wave structure and modulation instability analysis for coupled fractional Lakshmanan-Porsezian-Daniel equation with Kerr's law nonlinearity. [PDF]

Sci Rep
Aghazadeh A, Lakestani M.
europepmc   +1 more source

Efficient FORTRAN subprograms for the solution of elliptic partial differential equations. [PDF]

, 1975
Paul N. Swarztrauber, Roland A. Sweet
openalex   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

Advanced fractional soliton solutions of the Joseph-Egri equation via Tanh-Coth and Jacobi function methods. [PDF]

Sci Rep
Shakeel K, Baleanu D, Abbas M, Yousif MA, Mohammed PO, Abdullah FA, Abdeljawad T.   +6 more
europepmc   +1 more source

Some problems involving elliptic partial differential equations with mixed boundary conditions [PDF]

, 1962
C. C. Bartlett
openalex  

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source