Results 201 to 210 of about 233,511 (375)

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

open access: yesAdvanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang   +10 more
wiley   +1 more source

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

open access: yesAdvanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang   +9 more
wiley   +1 more source

Gross-Pitaevskii systems of fractional order with respect to multicomponent solitary wave dynamics. [PDF]

open access: yesSci Rep
Bilal M   +6 more
europepmc   +1 more source

Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis

open access: yesAdvanced Science, EarlyView.
Fumadó Navarro et al. present an optimized strategy to generate vascular‐like networks that infiltrate within cerebral organoids with promising signs of blood‐brain barrier characteristics, preserved stiffness, uniform morphology, enhanced media diffusion, and reduced necrotic core.
Josep Fumadó Navarro   +7 more
wiley   +1 more source

Deep Learning‐Assisted Rapid Bacterial Classification Based on Raman Spectroscopy of Bacteria Lysed by Acoustically Driven Fiber‐Tip Vibration

open access: yesAdvanced Science, EarlyView.
A novel acoustofluidic lysis technique based on a vibrating fiber‐tip is integrated with Raman spectroscopy and deep learning for rapid, label‐free bacterial classification. By exposing intracellular biomolecules, this method significantly enhances spectral resolution, enabling high‐accuracy classification with a 1D‐ResNet model.
Yukai Liu   +9 more
wiley   +1 more source

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