Results 241 to 250 of about 18,366,163 (311)

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou   +21 more
wiley   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

open access: yesAdvanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima   +18 more
wiley   +1 more source

Why the "<i>Y</i>" Becomes a "Trans-<i>Y</i>": Validation of the "Number <i>Y</i>" for Implant Height Prediction in Gender-Affirming Breast Augmentation Using Anatomical Implants. [PDF]

open access: yesAesthet Surg J Open Forum
Wellenbrock S   +8 more
europepmc   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

open access: yesAdvanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw   +4 more
wiley   +1 more source

A Single‐Capillary Open Microfluidic Probe for Robust and Versatile Spatial Multi‐Omics Using Ambient Mass Spectrometry Imaging

open access: yesAdvanced Science, EarlyView.
This study reports a knot‐shaped single‐capillary open microfluidic probe (Knot‐probe) for robust and versatile spatial omics, enabling ambient mass spectrometry imaging with high spatial resolution, throughput, and structure‐resolved capability. Knot‐probe mitigates the trade‐off between analytical performance and operational robustness, providing an ...
Xiangyu Zhu   +10 more
wiley   +1 more source

Strain‐Enhanced Ultrastretchable Semiconducting Polymer Fibers for Organic Electrochemical Transistors

open access: yesAdvanced Science, EarlyView.
The continuous fabrication of stretchable polymer semiconductor p(g2T‐T) fibers is realized via wet‐spinning. The p(g2T‐T) semiconductor fibers possess an efficient strain energy dissipation mechanism and unique strain‐enhanced electrical performance. They can be stretched to over 250% strain and exhibit an ultrahigh normalized transconductance of 276 ...
Zixu Chang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy