Results 171 to 180 of about 22,597,145 (371)
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
Advanced Healthcare Materials, EarlyView.A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li +8 more
wiley +1 more source
An Analysis of a Gear System Consisting of a Half-Elliptical Gear and a Noncircular Gear Wheel
, 1961 Keizo Nakagawa
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A remark on strong maximum principle for parabolic and elliptic systems [PDF]
, 1990 Xuefeng Wang
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Advanced Healthcare Materials, EarlyView.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Optimal boundary control for a time dependent thermistor problem
Electronic Journal of Differential Equations, 2009 An optimal control of a two dimensional time dependent thermistor problem is considered. The problem consists of two nonlinear partial differential equations coupled with appropriate boundary conditions which model the coupling of the thermistor to ...
Volodymyr Hrynkiv
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Advanced Healthcare Materials, EarlyView.Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Advanced Materials, EarlyView.Left‐ and right‐handed circularly polarized light emission (CPLE) is observed from chiral “hedgehog” particles (CHIPs) coated with a nanofilm of achiral perovskite, with spectroscopic bands specific to the perovskites and chirality specific to the template CHIPs. Careful analysis of optical activity indicates that the CPLE of perovskite luminescence is
Michael Veksler +7 more
wiley +1 more source
A nonexistence result for a system of quasilinear degenerate elliptic inequalities in a half-space
Electronic Journal of Differential Equations, 2002 We show that a system of quasilinear degenerate elliptic inequalities does not have non-trivial solutions for a certain range of parameters in the system.
Mokthar Kirane, Eric Nabana
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Nonoscillation and comparison theorems for a class of higher order elliptic systems
, 1976 Norio Yoshida
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