Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis
The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang +14 more
wiley +1 more source
Soliton dynamics and stability in resonant nonlinear Schrödinger systems with cubic quintic effects via enhanced modified extended tanh function method. [PDF]
Tarek A, Ahmed HM, Badra N, Samir I.
europepmc +1 more source
NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang +8 more
wiley +1 more source
A secure multi phase authentication protocol for cloud infrastructure using elliptic curve cryptography. [PDF]
Sivasankar R, Marikkannan M.
europepmc +1 more source
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
Parabolic-elliptic and indirect-direct simplifications in chemotaxis systems driven by indirect signalling. [PDF]
Bui LTT, Huynh TKL, Tang BQ, Tran BN.
europepmc +1 more source
Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl +7 more
wiley +1 more source
Dynamic soliton solutions and stability analysis of the (2+1)-dimensional Wazwaz Kaur Boussinesq equation using an efficient method. [PDF]
Elsonbaty NM +3 more
europepmc +1 more source
Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet +8 more
wiley +1 more source
CryptoShield-multilayered cryptographic framework for enhanced security and robust communication systems. [PDF]
Altaf M +4 more
europepmc +1 more source

