Results 281 to 290 of about 176,343 (312)

Strong and Fatigue‐Resistant Hydrogels via Poor Solvent Evaporation Assisted Hot‐Stretching for Tendon Repair

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
An anisotropic hydrogel (AHs) is prepared in this study. The strength of AHs can reach up to 33.14 ± 2.05 MPa, and it exhibits unique defect‐insensitive characteristics. Cracks can only deflect along the fiber alignment direction, demonstrating an interesting self‐protection function.
Huamin Li   +11 more
wiley   +1 more source

Symmetry Breaking in Meniscus Splitting: Effects of Boundary Conditions and Polymeric Membrane Growth

open access: yesAdvanced Science, EarlyView.
Meniscus splitting in the drying of a viscous polymer dispersion is investigated by focusing on nucleation of multiple nuclei with symmetry breaking and asynchronous nucleus formation. Controlled by spatial boundaries, the first nucleus is generated at a position shifted away from the space center and strongly facilitates the asynchronous second ...
Thi Kim Loc Nguyen   +4 more
wiley   +1 more source

Interfacial Polarization Switching in Al0.92Sc0.08N/GaN Heterostructures Grown by Sputter Epitaxy

open access: yesAdvanced Science, EarlyView.
Understanding the structural and electronic interface characteristics of ferroelectric Al1‐xScxN/GaN heterostructures is crucial for the development of novel transistor structures with integrated ferroelectric functionality. In this article, Niklas Wolff and co‐workers report on the interfacial switching mechanisms and reveal atomic and electronic ...
Niklas Wolff   +6 more
wiley   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

open access: yesAdvanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang   +9 more
wiley   +1 more source

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

open access: yesAdvanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong   +12 more
wiley   +1 more source

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