Results 31 to 40 of about 22,885,588 (357)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Quasilinear elliptic systems [PDF]

Annali di Matematica Pura ed Applicata (1923 -), 1978
The quasilinear elliptic system $$\sum\limits_{l{\text{ = 1}}}^n {\frac{\partial }{{\partial x_l }}\left\{ {\sum\limits_{j = 1}^N {\sum\limits_{m = 1}^n {C_{ij}^{lm} [x,U]\frac{{\partial U^j }}{{\partial x_m }} + B_i^l [x,U]} } } \right\} + F_i [x,U] = 0} $$
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A sub-super solution method to continuous weak solutions for a semilinear elliptic boundary value problems on bounded and unbounded domains

Electronic Research Archive
In this paper, we prove the existence of solutions for an elliptic system. More precisely, we combine the potential theory with the sub-super solution method and use the properties of the well-known Kato class to justify our existence results.
Abdeljabbar Ghanmi , Hadeel Z. Alzumi, Noureddine Zeddini   +2 more
doaj   +1 more source

Existence and multiplicity of solutions for a class of superlinear elliptic systems

Advances in Nonlinear Analysis, 2018
In this paper, we establish the existence and multiplicity of solutions for a class of superlinear elliptic systems without Ambrosetti and Rabinowitz growth condition. Our results are based on minimax methods in critical point theory.
Li Chun, Agarwal Ravi P., Wu Dong-Lun
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Existence and Non-Existence Results for Nonlocal Elliptic Systems via Sub-Supersolution Method

, 2016
In this paper, using a sub-supersolution argument, we prove an existence result on a positive weak solution for a class of nonlocal elliptic systems in bounded domains.
G. Afrouzi, N. T. Chung, S. Shakeri
semanticscholar   +1 more source

Oscillation criteria for elliptic systems [PDF]

Proceedings of the American Mathematical Society, 1971
Oscillation criteria are established for quasilinear elliptic partial differential systems of second order in unbounded domains of Euclidean space. The main departures from earlier investigations are: (1) systems of partial differential equations are considered; (2) the equations are nonlinear; (3) the matrices involved are not required to be positive ...
Allegretto, W., Swanson, C. A.
openaire   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Study on the generalized (p,q)$(p,q)$-Laplacian elliptic systems, parabolic systems and integro-differential systems

, 2016
In this paper, we present the abstract results for the existence and uniqueness of the solution of nonlinear elliptic systems, parabolic systems and integro-differential systems involving the generalized (p,q)$(p,q)$-Laplacian operator.
Li Wei, R. Agarwal, P. J. Wong
semanticscholar   +1 more source