Results 111 to 120 of about 3,943 (230)

Synthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosis [PDF]

, 2011
Several series of compounds that include the thienopyridine scaffold have been reported as inhibitors of known cancer therapeutic targets or as inhibitors of cell proliferation in tumor cell lines [1,2].
Abreu, Rui M.V., Alvelos, M. Inês, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., Lima, Raquel T., Pinto, Eugénia, Queiroz, Maria João R.P., Vale-Silva, Luís A., Vasconcelos, M. Helena   +8 more
core  

Tuning the surface coating of IONs toward efficient sonochemical tethering and sustained liberation of topoisomerase II poisons

International Journal of Nanomedicine, 2019
Hana Michalkova,1 Vladislav Strmiska,1 Jiri Kudr,1,2 Zuzana Skubalova,1 Barbora Tesarova,1 Pavel Svec,1 Lukas Richtera,1,2 Ondrej Zitka,1,2 Vojtech Adam,1,2 Zbynek Heger1,2 1Department of Chemistry and Biochemistry, Mendel University in Brno, Brno CZ-613
Michalkova H, Strmiska V, Kudr J, Skubalova Z, Tesarova B, Svec P, Richtera L, Zitka O, Adam V, Heger Z   +9 more
doaj  

Nemkovalens kölcsönhatások szerepe biológiai fontosságú vegyületek fényelnyelés hatására végbemenő folyamataiban = Effect of noncovalent interactions on the photoinduced processes of biologically important compounds [PDF]

, 2013
Feltártuk, hogy molekulák spontán önszerveződése komplexekké vagy jól definiált sztöchiometriájú aggregátumokká miként befolyásolja a fényelnyelést követő folyamatok kinetikáját és mechanizmusát.
Biczók, László, Megyesi, Mónika, Miskolczy, Zsombor Balázs   +2 more
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Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]

, 1986
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R., Cox, O., Elo, Hannu, Kovacic, Peter, Lumme, Paavo, Ryan, Michael D.   +5 more
core   +1 more source

Antimalarial activity of ellipticine

Phytomedicine, 2012
Pohlit, Adrian Martin, Silva, Luiz Francisco Rocha e, Henrique, Marycleuma Campos, Montoia, Andréia, Amorim, Rodrigo César das Neves, Nunomura, Sergio Massayoshi, Andrade Neto, Valter Ferreira de   +6 more
openaire   +3 more sources

Bone marrow stem cells incubated with ellipticine regenerate articular cartilage by attenuating inflammation and cartilage degradation in rabbit model. [PDF]

J Vet Sci, 2023
Hossain MA, Lim S, Bhilare KD, Alam MJ, Chen B, Vijayakumar A, Yoon H, Kang CW, Kim JH.   +8 more
europepmc   +1 more source

Les alcaloïdes d'Ochrosia silvatica (Apocynacées) [PDF]

, 1970
Cosson, J.P., Schmid, Maurice
core   +1 more source

Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol. [PDF]

RSC Adv, 2023
Lee S, Chao MW, Wu YW, Hsu CM, Lin TE, Hsu KC, Pan SL, Lee HY.   +7 more
europepmc   +1 more source

Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]

, 1994
Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L., George, S.G., Livingston, D.R.   +2 more
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Modulation of drug sensitivity in yeast cells by the ATP‐binding domain of human DNA topoisomerase IIα [PDF]

, 2017
Epipodophyllotoxins are effective antitumour drugs that trap eukaryotic DNA topoisomerase II in a covalent complex with DNA. Based on DNA cleavage assays, the mode of interaction of these drugs was proposed to involve amino acid residues of the catalytic
Benoit, Audrey, Gasser, Susan M., Leroy, Didier, Tsai‐Pflugfelder, Monika, Vilain, Nathalie   +4 more
core