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Ellipticine analogs: Oxygen and sulfur isosteres
Journal of Heterocyclic Chemistry, 1969AbstractOxaellipticine has been synthesized from 1,4‐dimethyldibenzofuran, by converting it to the 2‐aldehyde, forming the Schiff's base with aminoacetaldehyde diethyl acetal, and cyclizing this with 105%superphosphoric acid. Alternatively, tetrahydrodimethyldibenzofuran was formylated mainly at the 3‐position, and the 3‐(2‐nitrovinyl) derivative of ...
Allan N. Fujiwara +2 more
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A POSSIBLE MECHANISM OF ELLIPTICINE-INDUCED HEMOLYSIS
The Journal of Pharmacology and Experimental Therapeutics, 1976Ellipticine (E) [5,11-dimethyl-6H-pyrido-(4,3-b)-carbazole, NSC-71795] is an antineoplastic agent which is active against L1210 lymphocytic leukemia in mice. Preclinical toxicologic studies demonstrated hemolysis in dogs and monkeys following intravenous administration of 1.5 mg/kg. This finding prompted this investigation of the mechanism of hemolysis
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Syntheses in the ellipticine-olivacine series
Tetrahedron, 1981RICHARD BESSELIÈVRE +1 more
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Synthese industrielle en serie ellipticine. II
Tetrahedron, 1993Jean-Robert Dormoy, Alain Heymes
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Intercalative binding of ellipticine to DNA.
Cancer research, 1975Ellipticine (NSC 71795), a plant alkaloid with antitumor activity, is a weakly basic polycyclic molecule with dimensions similar to those of proflavin. Like proflavin, ellipticine exhibits hypocromic and bathochromic changes in absorption spectrum in the presence of DNA.
K W, Kohn +3 more
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Electrochemical behavior of ellipticine derivatives
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1981A. Anne, J. Moiroux
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An efficient synthesis of ellipticine
The Journal of Organic Chemistry, 1982Mark G. Saulnier, Gordon W. Gribble
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