Results 21 to 30 of about 3,943 (230)
International Journal of Electrochemical Science, 2013 The antineoplastic alkaloid ellipticine is a prodrug, the pharmacological efficiency of which is dependent on its cytochrome P450 (CYP)- and/or peroxidase-mediated activation to species forming DNA adducts in target tissues.
Jitka Poljaková +5 more
doaj +1 more source
International Journal of Electrochemical Science, 2013 The antineoplastic alkaloid ellipticine is a prodrug, the pharmacological efficiency of which is dependent on its cytochrome P450 (CYP)- and/or peroxidase-mediated activation in target tissues.
Iveta Vranová +5 more
doaj +1 more source
Effect of hydrogen bonding and complexation with metal ions on the fluorescence of luotonin A [PDF]
, 2013 Fluorescence characteristics of a biologically active natural alkaloid, luotonin A (LuA), were studied by steady-state and time-resolved spectroscopic methods.
Abraham +45 more
core +1 more source
International Journal of Electrochemical Science, 2014 The antineoplastic alkaloid ellipticine is a prodrug, of which the pharmacological efficiency is dependent on its cytochrome P450 (CYP)- and/or peroxidase-mediated activation to 12-hydroxy- and 13-hydroxyellipticine, which are both the metabolites ...
Marie Stiborova +7 more
doaj +1 more source
Pathogens, 2020 The pathogen Phytophthora infestans is responsible for catastrophic crop damage on a global scale which totals billions of euros annually. The discovery of new inhibitors of this organism is of paramount agricultural importance and of critical relevance ...
John J. Mackrill +6 more
doaj +1 more source
Stochastic models (cooperative and non-cooperative) for NMR analysis of the hetero-association of aromatic molecules in aqueous solution [PDF]
, 2006 Stochastic cooperative (STOCH-C) and non-cooperative (STOCH-NC) models have been developed for NMR analysis of the hetero-association of aromatic compounds in solution, in order to take into account all physically meaningful association reactions of ...
Davies, David B. +2 more
core +1 more source
Biomedicines, 2023 Molecular hybridization has emerged as the prime and most significant approach for the development of novel anticancer chemotherapeutic agents for combating cancer.
Ameer Fawad Zahoor +11 more
doaj +1 more source
Multiple inclusion complex formation of protonated ellipticine with cucurbit[8]uril: thermodynamics and fluorescence properties [PDF]
, 2016 The encapsulation of protonated ellipticine (EH+) in the cavity of cucurbit[8]uril (CB8) was studied in water at pH 4 with spectrophotometric, fluorescence spectroscopic and isothermal calorimetric measurements.
Biczók, László +2 more
core +2 more sources
Efficient and Simple Synthesis of 6-Aryl-1,4-dimethyl-9H-carbazoles
Molecules, 2008 A synthetic method for the preparation of 6-aryl-1,4-dimethyl-9H-carbazoles involving a palladium catalyzed coupling reaction of 1,4-dimethyl-9H-carbazole-6-boronic acids and (hetero)aryl halides is described.
Sylvain Rault +5 more
doaj +1 more source
Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: in vitro evaluation, cell cycle analysis and QSAR studies [PDF]
, 2011 Hepatocellular carcinoma (HCC) is a highly complex cancer, resistant to commonly used treatments and new therapeutic agents are urgently needed. A total of thirty-two thieno[3,2-b]pyridine derivatives of two series: methyl 3-amino-6-(hetero)arylthieno[3 ...
Abreu, Rui M. V. +7 more
core +1 more source