Results 41 to 50 of about 3,943 (230)
Ring D modifications of ellipticine. Part 1. New ellipticine derivatives from 1-cyano-6-methylellipticine. [PDF]
Tetrahedron, 1994 Abstract New ellipticine derivatives are synthesized by modification of the cyanogroup of 1-cyano-6-methylellipticine. This resulted in the information of 1-acetyl- and 1-acetamido-6-methylellipticine. Deprotonation of 1-cyano-6-methylellipticine under the influence of a Palladium catalyst leads to a new annelated ellipticine (9).
Boogaard, A.T. +2 more
openaire +3 more sources
Molecular Biology at the Quantum Level: Can Modern Density Functional Theory Forge the Path?
, 2012 Recent years have seen vast improvements in the ability of rigorous quantum-mechanical methods to treat systems of interest to molecular biology. In this review article, we survey common computational methods used to study such large, weakly bound ...
Kolb, Brian, Thonhauser, T.
core +1 more source
Experimental and Molecular Medicine, 2020 Osteoarthritis: Drug-induced stem cell differentiation shows therapeutic promise A novel method of generating healthy cartilage cells from stem cells could repair and regenerate joints and bones damaged by osteoarthritis.
Jiyun Lee +11 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2022 Toll-like receptor 3 (TLR3), as an important pattern recognition receptor (PRR), dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases.
Xiaohong Cen +9 more
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Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals [PDF]
, 2016 After a period of indifference, in which synthetic compounds were favored, there is an increasing interest in the study of the biological properties of plants and the active principles responsible for their therapeutic properties. Geranium molle L.
Barros, Lillian +7 more
core +2 more sources
From Synthesis to Therapeutics: Bioactive‐Coated Zein Nanoparticles in Drug Delivery
Biopolymers, Volume 117, Issue 2, March 2026.ABSTRACT Polymeric zein nanoparticles (ZNP), derived from corn protein, are biodegradable drug carriers with high stability and low synthesis costs. Their amphiphilic nature allows efficient encapsulation of both hydrophilic and lipophilic drugs, making them promising for drug delivery.
Milena Ferreira de Lima +8 more
wiley +1 more source
Estrutura e propriedades de elipticinas Structure and properties of ellipticines
Química Nova, 2005 The ellipticines constitute a broad class of molecules with antitumor activity. In the present work we analyzed the structure and properties of a series of ellipticine derivatives in the gas phase and in solution using quantum mechanical and Monte Carlo ...
José J. V. Cirino +5 more
doaj +1 more source
Journal of Nanobiotechnology, 2020 Background Currently, the diagnosis and treatment of neuroblastomas—the most frequent solid tumors in children—exploit the norepinephrine transporter (hNET) via radiolabeled norepinephrine analogs.
Yazan Haddad +14 more
doaj +1 more source
, 2012 A well-defined notion of chemical compound space (CCS) is essential for gaining rigorous control of properties through variation of elemental composition and atomic configurations. Here, we review an atomistic first principles perspective on CCS.
von Lilienfeld, O. A.
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Development of dairy beverages functionalized with pure ergosterol and mycosterol extracts: an alternative to phytosterol-based beverages [PDF]
, 2017 In the present work, Agaricus bisporus extracts obtained by ultrasound-assisted extraction (UAE), and ergosterol, were incorporated into dairy beverages at concentrations mimicking commercial phytosterol-added yogurts, to work as alternatives.
Barreiro, M.F. +7 more
core +1 more source