Results 51 to 60 of about 3,943 (230)
Cancer Medicine, Volume 15, Issue 3, March 2026.Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian +3 more
wiley +1 more source
Frontiers in Microbiology, 2020 Extraintestinal pathogenic Escherichia coli (ExPEC) strains are the cause of a majority of human extraintestinal infections globally, resulting in enormous direct economic and medical costs.
Hao Lu +32 more
doaj +1 more source
Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]
, 2013 The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core
Anti-tumour heterocycles : part 16 : the synthesis of 7,10-dimethoxyellipticine and its pyrrolo[2,3-f]carbazole and pyrrolo[3,2-f] analogues [PDF]
, 1997 The final examples in our ellipticine/pyrrolocarbazole synthesis programme are 7,10-dimethoxyellipticine 1a and the corresponding pyrrolocarbazoles 2a and 3a which have been synthesised from 4,6 ...
Campos, Ana M. F. Oliveira +5 more
core +1 more source
Pathogens, 2020 The pathogen Phytophthora infestans is responsible for worldwide catastrophic crop damage and discovery of new inhibitors of this organism is of paramount agricultural and industrial importance.
Mary L. McKee +6 more
doaj +1 more source
Nonomuraea monospora sp. nov., an actinomycete isolated from cave soil in Thailand, and emended description of the genus Nonomuraea [PDF]
, 2012 A novel actinomycete, designated strain PT708T, was isolated from cave soil collected in Pha Tup Cave Forest Park, Nan province, Thailand. It produced compounds with antimicrobial and anticancer activities.
Lumyong, S. +3 more
core +1 more source
Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel +9 more
wiley +1 more source
Synthesis of highly substituted diphenylacetamides and diphenylsulfonamides by the goldberg coupling reaction [PDF]
, 2000 We report the synthesis and characterisation of multisubstituted diphenylacetamides, diphenylsulfonamides and diphenylamines (and some observations on cyclisation of the last).Fundação para a Ciência e a Tecnologia (FCT)ICCTI and CRUP (Portugal) and the ...
Campos, Ana M. F. Oliveira +3 more
core +1 more source
Chemistry – A European Journal, Volume 31, Issue 72, December 23, 2025.The REG1CP‐derived RNA oligonucleotide SL15P adopts a parallel G‐quadruplex (rGQ) structure. In this study, we investigate the effect of several well‐characterized ligands, originally developed for DNA GQs, on the RNA counterpart, with the aim of evaluating their binding ability and specific binding modes.
Giuseppe Satta +2 more
wiley +1 more source
International Journal of Nanomedicine, 2021 Michalkova H, Strmiska V, Kudr J, et al. Int J Nanomedicine. 2019;14:7609–7624The authors have advised due to an error at the time of figure assembly, Figure 1D on page 7614 and Figure 6A on page 7621 is incorrect. Read the ...
Michalkova H +9 more
doaj