Results 101 to 110 of about 10,784 (286)

Small ELMs - A promising reactor scenario

open access: yes, 2019
The foreseen operational scenario for future fusion devices is the high confinement mode, which is characterized by a strong increase in confinement due to the formation of a transport barrier at the plasma edge.
Harrer, Georg
core   +3 more sources

Progress and issues in understanding the physics of ELM dynamics, ELM mitigation, and ELM control

open access: yesJournal of Physics: Conference Series, 2008
Recent experimental progress in understanding the dynamics of type I ELM, small/no ELM regimes to achieve ELM mitigation and active ELM controls is reviewed. As for the type I ELM dynamics, the smaller growth rate of the ELM precursor relative to the Alfven frequency, the importance of ELM filaments to evaluate the ELM heat load, the evolution of ...
openaire   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

open access: yesAdvanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu   +11 more
wiley   +1 more source

Elms, Berwin Estate

open access: yes, 2010
Front entrance of The Elms.
Ernst Studio
core   +1 more source

On fast-ion transport induced by edge localized modes

open access: yesNuclear Fusion
Fast ions in a tokamak device exhibit a notable acceleration phenomenon during edge localized modes (ELMs). Presented here is an analytical analysis of the phase space transport of fast ions induced by ELMs.
Haotian Chen, Wei Chen
doaj   +1 more source

ALDH2 Suppresses Ferroptosis and Promotes Bortezomib Resistance in Multiple Myeloma Through the KEAP1‐NRF2 Feedback Loop

open access: yesAdvanced Science, EarlyView.
ALDH2, which is overexpressed in multiple myeloma, competitively binds KEAP1 to stabilize NRF2 by blocking its ubiquitin‐proteasomal degradation. Stabilized NRF2 translocates into the nucleus to upregulate the expression of GPX4. In parallel, NRF2 binds to the ALDH2 promoter to regulate its transcription, forming a positive feedback loop that represses
Ruonan Shao   +10 more
wiley   +1 more source

Elms (The)

open access: yes, 1939
Scan from a black and white photo of the Elms Stable.https://digitalcommons.library.umaine.edu/univ_photos/1139/thumbnail ...

core  

Combined Immune‐Peptide Nanofiber with HSP70/AKT/mTOR Axis Blockade Enhances Photothermal Immunotherapy, Inhibiting Tumor Growth and Recurrence

open access: yesAdvanced Science, EarlyView.
A carrier‐free peptide‐guided PSP@IR‐CF3 nanofiber system integrates PD‐L1 targeting and photothermal immunotherapy for enhanced cancer treatment. By revealing PTIT‐induced activation of the HSP70/AKT/mTOR pathway and incorporating mTOR inhibition, this strategy effectively overcomes therapeutic resistance and prevents tumor recurrence, providing a ...
Xinyu Zhang   +11 more
wiley   +1 more source

Impact of lower hybrid wave injection on edge localized modes in the HL-3 tokamak

open access: yesNuclear Fusion
Experiments assessing edge localized mode (ELM) control with lower hybrid wave (LHW) injection were carried out in the newly operational HL-3 tokamak for the first time, and the experimental results demonstrated that ELMs could be effectively suppressed ...
Y.M. Zhang   +18 more
doaj   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

open access: yesAdvanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen   +13 more
wiley   +1 more source

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