Results 91 to 100 of about 75,287 (266)

Maintenance Therapy with Chidamide Decreases the Relapse in Fusion Gene-Positive AML Patients with MRD-Positive or ELN-High Risk [PDF]

, 2023
Guopan Yu, Zhao Yin, Jixian Huang, Huiqing He, Xuejie Jiang, Hongsheng Zhou, Pengcheng Huang, Yu Zhang   +7 more
openalex   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

Clinical Genetics, EarlyView.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li, Xin Hou, Xiangyu Wang, Juan Li, Li Li, Xiangyi Ma   +5 more
wiley   +1 more source

AN EXPERIENCE OF IMPLEMENTING LIMS SYSTEM IN THE BIOANALYTICAL LABORATORY (PART 1)

Разработка и регистрация лекарственных средств, 2019
Center of Pharmaceutical Analytics purchased and installed LabWare LIMS laboratory information system, LabWare ELN electronic laboratory journals from LabWare company.
A. A. Krylatova, I. E. Shohin, A. S. Kardashin   +2 more
doaj  

ELN risk stratification and outcomes in secondary and therapy-related AML patients consolidated with allogeneic stem cell transplantation [PDF]

, 2020
Madlen Jentzsch, Juliane Grimm, Marius Bill, Dominic Brauer, Donata Backhaus, Karoline Goldmann, Julia Schulz, Dietger Niederwieser, Uwe Platzbecker, Sebastian Schwind   +9 more
openalex   +1 more source

Improvements in Real‐World Survival in the Setting of a Recent Paradigm Shift in Acute Myeloid Leukemia Treatment

European Journal of Haematology, EarlyView.
ABSTRACT Therapeutic options for newly diagnosed (ND) acute myeloid leukemia (AML) have increased in recent years, leading to a shift in the treatment paradigm from conventional, intensive chemotherapy toward targeted and less intensive therapy. Since 2017, there has been a surge in FDA approvals for novel therapies, including small molecule inhibitors
Thuy N. Ho, Patrick Willard, Graeme F. Murray, Li Liu, Nolan Wages, Hyun Lee, Keri R. Maher   +6 more
wiley   +1 more source

Phenotypic findings associated with variation in elastin

HGG Advances
Summary: Variation in the elastin gene (ELN) may contribute to connective tissue disease beyond the known disease associations of supravalvar aortic stenosis and cutis laxa.
Anne Justice, Melissa A. Kelly, Gary Bellus, Joshua D. Green, Raza Zaidi, Taylor Kerrins, Navya Josyula, Teresa R. Luperchio, Beth A. Kozel, Marc S. Williams   +9 more
doaj   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Effect of linseed (Linum usitatissimum) integration on the productive and reproductive performance of female rabbits

African and Mediterranean Agricultural Journal - Al Awamia
Various sources of omega-3 (n-3) fatty acids can affect multiple aspects of breeding female. This study investigated the effects of dietary substitution with extruded linseed on the productive and reproductive performance in female rabbits.
Nour Elhouda Fehri, Safa Bejaoui, Gabriele Brecchia, Bayrem Jemmali   +3 more
doaj   +1 more source

Outcomes of therapy‐related non‐core binding factor acute myeloid leukemia with venetoclax‐based therapies [PDF]

Hemasphere
Abstract Prognosis in therapy‐related acute myeloid leukemia (T‐AML) remains poor, but understanding outcomes with venetoclax (VEN)‐based therapy is relevant. We retrospectively analyzed 317 adult patients with newly diagnosed T‐AML focusing on lower intensity therapy (LIT) VEN‐containing regimens.
Senapati J, Croden J, Garcia‐Manero G, Takahashi K, Daver N, Kadia T, Borthakur G, Short N, Jabbour E, Haddad F, Marvin‐Peek J, Abbas H, Bose P, Tang G, Loghavi S, Shpall E, Ramdial J, Popat U, Champlin R, Ravandi F, Kantarjian H, Dinardo C.   +21 more
europepmc   +2 more sources