Results 161 to 170 of about 1,967 (171)
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Elp1‐Mediated Mechanisms Underlying Trigeminal Ganglion Development

The FASEB Journal, 2022
The trigeminal nerve is the largest of the cranial nerves and relays sensations of pain, touch, and temperature from the face and head back to the brain. Cell bodies for this nerve are positioned in the trigeminal ganglion, which arises from the coalescence of neurons and supporting glia derived from two important embryonic cell ...
Margaret Hines, Lisa Taneyhill
openaire   +1 more source

Neural Crest‐Specific Elp1 Deletion Disrupts Trigeminal Ganglion Development in a Model of Familial Dysautonomia

The FASEB Journal, 2022
Neurons in the trigeminal ganglion relay sensory information from the face and oral cavity to the brain. The trigeminal ganglion is unique in its complexity, containing a mixed population of modality‐specific (i.e., touch, pain) neurons derived from both neural crest and placodal precursors.
Carrie Leonard, Lisa Taneyhill
openaire   +1 more source

Elp1‐dependent Shp1 Phosphatase Regulation and its Essential Role in Familial Dysautonomia Pathogenesis

The FASEB Journal, 2018
Familial Dysautonomia (FD; Riley‐Day Syndrome; HSAN3) is a rare heritable disease characterized by debilitating sensory and sympathetic neuropathy. It is caused by a germline mutation of the Elp1 gene that leads to exon mis‐splicing, nonsense‐mediated truncation of the Elp1 protein and loss of Elp1 protein primarily in sympathetic and nociceptive ...
openaire   +1 more source

Gene Expression of Cotesiaplutellae Bracovlrus EP1-like Protein (CpBV-ELP1) in Parasitized Diamondback Moth, Plutellae xylostella

Journal of Asia-Pacific Entomology, 2005
Abstract A genome project has been launched and aims to sequence total genome of Cotesia plutellae bracovirus (CpBV). This on-going research has identified several open reading frames (ORFs) including an EPl-like protein (ELP1). This study was intended to analyze gene expression of CpBV-ELPl in the parasitized diamondback moth, Plutella xylostella ...
Keewoo Lee   +5 more
openaire   +1 more source

EXTH-20. Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

Neuro-Oncology
Abstract Germline loss-of-function (LOF) variants in Elongator acetyltransferase complex subunit 1 (ELP1) are the most prevalent predisposing genetic events observed in medulloblastoma (MB), accounting for 30% of the Sonic hedgehog (SHH) 3 subtype.
Shiekh Tanveer Ahmad   +36 more
openaire   +1 more source

Insect Resistance of Tobacco Plant Expressing CpBV-ELP1 Derived from a Polydnavirus

Korean Journal of Applied Entomology, 2017
Eunseong Kim, Yonggyun Kim
openaire   +1 more source

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