Results 41 to 50 of about 9,063 (217)

New inflammatory indicators: association of high eosinophil-to-lymphocyte ratio and low lymphocyte-to-monocyte ratio with smoking

Journal of International Medical Research, 2019
Objective Smoking has been proven to increase systemic inflammation in previous studies using different biomarkers. The eosinophil-to-lymphocyte ratio (ELR), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR) are new indicators ...
Yusuf Çekici, Mücahid Yılmaz, Özlem Seçen   +2 more
doaj   +1 more source

Early lymphocyte recovery after allogeneic transplantation of hematopoietic stem cells in patients with haematological malignancies: a single-centre experience [PDF]

Journal of Biomedical & Clinical Research
Introduction: Allogeneic hematopoietic stem cell transplantation (AlloHSCT) is a therapeutic method for the treatment of many malignant and non-malignant hematological diseases but is still associated with significant morbidity and mortality.
Kameliya Kostadinova, Krasen Venkov, Yonka Lazarova, Emilia Naseva, Ivan Tonev   +4 more
doaj   +3 more sources

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Comparison of two modes of long-term ECG monitoring to assess the efficacy of catheter ablation for paroxysmal atrial fibrillation

Biomedical Papers, 2019
Aims: Optimal ECG monitoring in detecting recurrences of atrial fibrillation (AF) or atrial tachycardia (AT) after catheter ablation has not been well established.
Jan Chovancik, Veronika Bulkova, Dan Wichterle, Ondrej Toman, Lukas Rybka, Jaroslav Januska, Jindrich Spinar, Martin Fiala   +7 more
doaj   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Empirical Legal Research in Europe: Prevalence, Obstacles, and Interventions [PDF]

, 2018
Empirical Legal research (ELR) has become well established in the United States, whereas its popularity in Europe is debatable. This article explores the popularity of ELR in Europe.
Sverdlov, S. (Shahar), Buck, G. (Gabriela), Buck, Gabriela, van Dijck, Gijs; id_orcid, Dijck, G. (Gijs) van, Sverdlov, Shahar   +5 more
core   +1 more source

Exploring the diagnostic value of eosinophil-to-lymphocyte ratio to differentiate Kawasaki disease from other febrile diseases based on clinical prediction model

Scientific Reports, 2023
Kawasaki disease (KD) is a febrile disease that affects children under 5 years of age and leads to serious cardiovascular complications such as coronary artery disease.
Xin Guo, Jinwen Liao, Xue Fan, Mingguo Xu   +3 more
doaj   +1 more source

Improving the Credibility of Empirical Legal Research: Practical Suggestions for Researchers, Journals and Law Schools

Law, Technology and Humans, 2021
Fields closely related to empirical legal research (ELR) are enhancing their methods to improve the credibility of their findings. This includes making data, analysis codes and other materials openly available on digital repositories and preregistering ...
Jason M Chin, Alexander C DeHaven, Tobias Heycke, Alexander O Holcombe, David T Mellor, Justin T Pickett, Crystal N Steltenpohl, Simine Vazire, Kathryn Zeiler   +8 more
doaj   +1 more source

From bodyweight to biomarkers: Season‐associated metabolic, endocrine and haematological shifts in breeding stallions

Equine Veterinary Journal, EarlyView.
Abstract Background Breeding stallions are subjected to sustained seasonal metabolic, endocrine, and immune demands requiring systemic energy engagement. Prospective longitudinal data in the same individuals are limited. Objectives To screen adaptive responses of breeding stallions of clinical relevance through longitudinal characterisation of temporal
Maria Grazia Cappai, Morrone Sarah, Senes Alice, Taras Andrea, Biggio Giampaolo, Cherchi Raffaele   +5 more
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source