Results 31 to 40 of about 589 (105)

Eltrombopag for the Treatment of Poor Graft Function Following Haematopoietic Cell Transplantation: Real-Life Data

Balkan Medical Journal, 2023
Background: Eltrombopag has an off-label indication for haematopoietic cell transplantation in patients experiencing delayed thrombocyte recovery and/or thrombocytopaenia.
Ekin Kırcalı, Güldane Cengiz Seval, Cemaleddin Öztürk, Hülya Yılmaz, Derya Koyun, Sinem Civriz Bozdağ, Selami Koçak Toprak, Pervin Topçuoğlu, Önder Arslan, Muhit Özcan, Taner Demirer, Osman İlhan, Günhan Gürman, Meral Beksaç, Meltem Kurt Yüksel   +14 more
doaj   +1 more source

Myelodysplastic Syndromes: 2026 Update on Diagnosis, Risk‐Stratification and Management

American Journal of Hematology, Volume 101, Issue 9, Page 2393-2411, September 2026.
ABSTRACT Disease Overview The myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid disorders characterized by peripheral blood cytopenias and increased risk of transformation to acute myelogenous leukemia (AML). MDS occurs more frequently in older males and in individuals with prior exposure to cytotoxic therapy.
Guillermo Garcia‐Manero
wiley   +1 more source

Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag

Case Reports in Cardiology, 2019
Background. Eltrombopag, a nonpeptide thrombopoietin receptor agonist (TPO-RA), has been reported to be an effective therapy for chronic immune thrombocytopenia (ITP).
Terumori Satoh, Masao Saotome, Kenichiro Suwa, Hayato Ohtani, Yasuyuki Nagata, Takaaki Ono, Yuichiro Maekawa   +6 more
doaj   +1 more source

Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m⁶A Methylation of RNA in Acute Myeloid Leukemia Cells

Pharmaceuticals, 2022
N6A-methyladenosine (m6A) post-transcriptional modification, the most abundant internal RNA modification, is catalyzed by the METTL3-14 methyltransferase complex. Recently, attention has been drawn to the METTL3-14 complex regarding its significant roles
Je-Heon Lee, Namjeong Choi, Subin Kim, Mi Sun Jin, Haihong Shen, Yong-Chul Kim   +5 more
doaj   +1 more source

Successfully performed video capsule endoscopy in an 8‐month‐old infant weighing 7.5 kg

JPGN Reports, Volume 7, Issue 3, Page 474-476, August 2026.
Abstract Video capsule endoscopy (VCE) is a well‐established diagnostic tool for examining the small bowel. Limited data exist on its use in infants. To our knowledge, we present the first detailed case of a successful PillCam®SB3‐VCE performed in an 8‐month‐old infant weighing 7.5 kg with suspected small bowel bleeding following allogeneic ...
Paul‐Christoph Zeisler, Robert Thimme, Ulrike Teufel‐Schaefer, Michael Schultheiß   +3 more
wiley   +1 more source

Efficacy of eltrombopag in combination with recombinant human thrombopoietin (rhTPO) for lymphoma patients with chemotherapy-induced thrombocytopenia

Frontiers in Pharmacology
PurposeTo observe the efficacy and adverse reactions of eltrombopag combined with rhTPO in the treatment of lymphoma patients with chemotherapy - induced thrombocytopenia (CIT).MethodsA retrospective study was performed on the clinical data of 61 ...
Qiuhua Zhu, Wenbin Zeng, Lanlan Zhou, Shimei Yang, Shiqiu Qiu, Mingjie Li, Yanan Liu, Chaolun Chen, Yanmin Gao, Zebing Guan, Xueyi Pan   +10 more
doaj   +1 more source

Efficacy and Safety of rhIL‐11 in the Treatment of Cancer Therapy‐Induced Thrombocytopenia: A Multicenter Retrospective Study

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Objective This real‐world study aimed to investigate the cancer therapy‐induced thrombocytopenia (CTIT) profile and evaluate the efficacy and safety of recombinant human interleukin‐11 (rhIL‐11) in its management. Methods Retrospective analysis included 12,431 CTIT patients treated with rhIL‐11 across 58 Chinese centers (July 2023–June 2024 ...
Yingmei Wen, Yi Dong, Yingge Li, Jinxiong Xia, Zheming Liu, Yuanyuan Wang, Ruibin Li, Ming Wang, Bin Xu, Dongling Tang, Lulu Chen, Huibo Zhang, Qibin Song, Yi Yao   +13 more
wiley   +1 more source

Efektivitas Eltrombopag dalam Penanganan Anemia Aplastik Berat pada Anak

Sari Pediatri
Latar belakang. Efektivitas pemberian eltrombopag pada kasus anemia aplastik berat pada anak masih kontroversial. Tujuan. Melakukan telaah kritis untuk melihat efektivitas pemberian eltrombopag dalam penanganan anemia aplastik berat pada anak.
Mega Septiana, Teny Tjitra Sari
doaj   +1 more source

Use of Eltrombopag in Improving Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation

Case Reports in Oncology, 2018
Eltrombopag is a thrombopoietin agonist and has been used in aplastic anemia and post-transplantation thrombocytopenia. The c-MPL receptor is present on hematopoietic stem cells.
Samip Master, Ashish Dwary, Richard Mansour, Glenn M. Mills, Nebu Koshy   +4 more
doaj   +1 more source

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu, Zining Wang, Jiaming Hu, Chunyan Liu, Rong Fu   +4 more
wiley   +1 more source