Results 171 to 180 of about 18,144,236 (296)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Exploring an EM-algorithm for banded regression in computational neuroscience. [PDF]

open access: yesImaging Neurosci (Camb)
Fuglsang SA   +4 more
europepmc   +1 more source

Bidirectional Soft Catalysts for Improved Power Performance of Li‐S Batteries

open access: yesAdvanced Science, EarlyView.
A soft polymer‐metal catalyst is integrated into the binder to create a catalytically active microenvironment that accelerates bidirectional sulfur redox kinetics in lithium‐sulfur batteries. A model polyvinyl alcohol‐Cu catalyst enables high areal capacities at demanding current densities and stable cycling in pouch‐cell prototypes at 0.5 C, achieving
Maleesha M. Nishshanke   +7 more
wiley   +1 more source

EM algorithm in Gaussian copula with missing data

open access: yesComputational Statistics & Data Analysis, 2016
Wei Ding, P. X. Song
semanticscholar   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

open access: yesAdvanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou   +6 more
wiley   +1 more source

Prediction of earthquake hazard by hidden Markov model (around Bilecik, NW Turkey)

open access: yesOpen Geosciences, 2014
Can Ceren, Ergun Gul, Gokceoglu Candan
doaj   +1 more source

Inference in Mixed Proportional Hazard Models with K Random Effects [PDF]

open access: yes
A general formulation of Mixed Proportional Hazard models with K random effects is provided. It enables to account for a population stratified at K different levels.
Guillaume Horny.
core  

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen   +13 more
wiley   +1 more source

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