Results 51 to 60 of about 104,844 (357)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Sophia: The Female Aspect of Christ in Origen of Alexandria
Open TheologyThis article examines the feminine aspect of Sophia, a significant title for Christ in Origen of Alexandria’s theology. It investigates whether Origen recognized and utilized Sophia’s femininity to develop a Christology that incorporates female elements ...
Jacobsen Anders-Christian
doaj +1 more source
Constraining Radon Backgrounds in LZ [PDF]
, 2017 The LZ dark matter detector, like many other rare-event searches, will suffer from backgrounds due to the radioactive decay of radon daughters. In order to achieve its science goals, the concentration of radon within the xenon should not exceed $2\mu$Bq ...
Busenitz, J. +10 more
core +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
No Ontological Leaps: A Primer on Scientific Materialism [PDF]
Integral Review, 2011 When the issue is intelligence in nature, arguments about whether science supports neo-Darwinian theory or intelligent design miss the point. The details of evolution or the structure of the brain are irrelevant because biology and neuroscience have ...
Christian de Quincey
doaj
MYSTICAL-METAPHYSICS: THE TYPE OF ISLAMIC PHILOSOPHY IN NUSANTARA IN THE 17th-18th CENTURY
Jurnal Ushuluddin, 2019 This article is aimed to analyze the geneology of the origin of philosophical thinking of scientists in Nusantara, especially the one which developed in the seventeenth and the eighteenth century, also included the themes which developed in those periods
Humaidi Humaidi
doaj +1 more source
Creation and Divine Providence in Plotinus [PDF]
, 2015 In this paper, we argue that Plotinus denies deliberative forethought about the physical cosmos to the demiurge on the basis of certain basic and widely shared Platonic and Aristotelian assumptions about the character of divine thought.
Noble, Christopher, Powers, Nathan
core
The Spectrum of Radium Emanation
Nature, 1908 IN NATURE of July 9 a letter from Prof. Rutherford appears giving an excellent corroboration of measurements of the spectrum of radium emanation which we communicated to the Royal Society on July 1.
W. Ramsay, A. T. Cameron
semanticscholar +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source